Depression (Adult and Geriatric) Clinical Trials
A listing of Depression (Adult and Geriatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 155 clinical trials
The Kunshan Elderly Health Study
The Kunshan Elderly Health Study (KEHS) is a community-based prospective cohort study of chronic disease, mortality and associated factors among elderly adults in Kunshan, Eastern China.
- 5 views
- 10 Dec, 2021
- 1 location
Neural Circuit Biomarkers of Transcranial Magnetic Stimulation Study
The objective of this observational study is to test whether neuroimaging biomarkers of repetitive transcranial magnetic stimulation (TMS) can be prospectively replicated in a large ecologically valid sample. We focus on cognitive network connectivity as a predictive biomarker of the clinical effect of TMS, and as a response biomarker of …
- 0 views
- 22 Apr, 2022
- 1 location
Early Life Stress and Depression: Molecular and Functional Imaging
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD). For some individuals, childhood adversity has negative psychological and medical consequences; others preserve mental and physical health despite such experiences (they are resilient). In spite of this, little is known …
- 0 views
- 09 Dec, 2021
- 1 location
Computational Psychiatric Approach for Prognosis of Medication-Resistant Depression
The purpose of this research is to investigate how the brain changes in patients undergoing electroconvulsive (ECT) treatment for depression. Subjects will be invited to be in this study because (1) they are a patient about to receive ECT treatment for depression, or (2) they are a patient diagnosed with …
- 289 views
- 28 Oct, 2022
- 1 location
Improving Brain Stimulation Through Imaging (IBSI)
Repetitive pulse transcranial magnetic stimulation (rTMS) is a noninvasive treatment that involves stimulating the brain; however, treatment benefit depends on placing a TMS coil in the correct place on the head to reach critical brain regions below. Clinicians typically use scalp-based targeting, a process in which rather than using MRI …
- 466 views
- 07 Oct, 2022
- 1 location
Resting-state Functional Connectivity Throughout a Course of iTBS in Major Depression
This study aims to investigate changes in functional connectivity over a four week treatment course with intermittent theta burst stimulation (iTBS) in patients with major depressive disorder (MDD). To this end, seven weekly resting-state fMRI (rs-fMRI) scans at 7 tesla (7T) will precede, accompany and follow the iTBS treatment course. …
- 0 views
- 04 Jun, 2022
- 1 location
Pharmacokinetics and Pharmacodynamics of Oral Sertraline Before and After Bariatric Surgery (ANTILOP)
Volunteers with a prescription of oral sertraline who have been scheduled to bariatric surgery in either Norrkping/Sweden or Lindesberg/Sweden will be asked to participate in a observational study. The aim of this study is to evaluate the absorption and the effect and side effects of sertraline in volunteers 8 weeks …
- 2 views
- 28 Feb, 2022
- 2 locations
Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862 (TREND-3)
Depression doubles the risk of death in patients with coronary heart disease (CHD), but so far, there is insufficient evidence that we can reduce the risk of death by treating depression. This study will investigate the cardiac risk markers that are associated with depression symptoms that remain despite treatment, and …
- 0 views
- 20 Apr, 2022
- 1 location
The Danish Neuropsychological Study on the Adverse Effects of ECT
The main purpose of this study is to determine whether electroconvulsive therapy (ECT) causes any structural or functional brain changes and thus indicating its mechanism of action. The second aim is to find predictors of an immediate response, sustained remission, relapse and side-effects. Thirdly, this study aims to explore whether …
- 0 views
- 17 Feb, 2021
- 1 location
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Depression
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records
- 136 views
- 28 Feb, 2022
- 1 location