Depression (Adult and Geriatric) Clinical Trials

A listing of Depression (Adult and Geriatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 51 clinical trials
Featured trial
Depression - Treatment Resistant

Still feeling symptoms of Depression after having taken a prescription Antidepressant?  If so, participating in our medical research study of an investigational drug may be an option for you.

depressive episode
depressive symptoms
depressed mood
antidepressants
  • 911 views
  • 16 Dec, 2022
  • 1 location
Featured trial
Depression

Depression...It interferes with the ability to work, eat, sleep and enjoy life.  If you are experiencing symptoms of depression, a clinical research study may be your next step.  

depressive symptoms
depressed mood
  • 703 views
  • 16 Dec, 2022
  • 1 location
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents (P2P)

PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental …

behavior therapy
psychiatric disorder
depressive symptoms
Accepts healthy volunteers
depressive disorder
  • 47 views
  • 04 Oct, 2022
  • 1 location
Collaboration Leading to Addiction Treatment and Recovery From Other Stresses (CLARO)

Collaboration Leading to Addiction Treatment and Recovery from Other Stresses (CLARO) is a five-year project that tests whether delivering care using a collaborative model helps patients with both opioid use disorders and mental health disorders.

opioid
depressed mood
depression
  • 37 views
  • 07 Oct, 2022
  • 3 locations
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

This study is comprised of three separate pharmacogenetic trials grouped into a single protocol due to similarities in the intervention, the hypotheses, and the trial design. The three trials are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the …

acute pain
opioid
depressive symptoms
headache
depressed mood
  • 299 views
  • 04 Oct, 2022
  • 10 locations
Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and Adults

Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the project is to document, in pediatric anxiety disorders and major depression, perturbations in brain systems mediating attention biases, fear conditioning, emotional memory, and response …

mood disorder
behavior therapy
social phobia
behavior modification
depressive symptoms
  • 736 views
  • 21 Oct, 2022
  • 1 location
A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High-Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE)

RATIONALE: Participating in a physical activity program designed to increase free time physical activity and receiving written health education materials may influence the chance of cancer recurring as well as impact on physical fitness, psychological well-being and the quality of life of patients who have undergone surgery and chemotherapy for …

cancer
cancer treatment
fatigue
x-rays
immunomodulators
  • 598 views
  • 22 Oct, 2022
  • 47 locations
Enhanced, EHR-facilitated Cancer Symptom Control Pragmatic Clinical Trial (E2C2)

This early phase I trial investigates enhanced, electronic health record (EHR)-facilitated cancer system control. Cancer and its treatment are often associated with severe, disabling symptoms that have been causally linked to diminished survival, increased healthcare utilization, degraded quality of life, unemployment, and non-adherence to recommended cancer treatments. Collaborative case management …

cancer
fatigue
depressed mood
depression
solid tumor
  • 31 views
  • 04 Oct, 2022
  • 1 location
Depression Screening in Black Churches

The overall aim of this study is to employ Community Health Workers (CHWs) to screen for depression in 30 Black churches and compare the effectiveness of Screening, Brief Intervention, and Referral to Treatment (SBIRT) (Intervention arm) to Referral As Usual (Control arm) on treatment engagement for depression. The investigators will …

depression screening
depressed mood
depressive symptoms
  • 0 views
  • 04 Oct, 2022
  • 1 location
Reducing Depressive Symptoms Among Rural African Americans (REJOICE)

Rural African Americans are disproportionately impacted by social stressors that place them at risk for experiencing elevated depressive symptoms. This project will test the effectiveness of a culturally adapted behavioral activation intervention (REJOICE) for use within rural African American churches. Further, this project will gather data on strategies necessary to …

depressive symptoms
  • 267 views
  • 20 Oct, 2022
  • 1 location