Search Medical Condition
Please enter condition
Please choose location from dropdown

Periodontitis Clinical Trials

A listing of Periodontitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (69) clinical trials

Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment

The aim of the present study is to evaluate the clinical and microbiological efficacy of moxifloxacin or amoxicillin plus metronidazole in one-stage scaling and root planing in treating generalized aggressive periodontitis. Forty five subjects will be randomly allocated to 3 treatment groups. Subgingival plaque samples will be analysed for cultivable ...

Phase

Tooth Extraction in Patients With Atrial Fibrillation in Use of New Oral Anticoagulants

The sample will be divided into three groups according to the pharmacokinetics of the oral anticoagulant: rivaroxaban 1x/day (group 1); dabigatran and apixabana 2x/day (group 2) and warfarin (control group). Extraction of one to three teeth will be scheduled, in the valley of the new oral anticoagulants' concentration, considered the ...

Phase N/A

Efficacy of PRF With M-MIST in the Treatment of Intrabony Defects

INTRODUCTION In the last two decades, some clinical investigators have focused their interest on the development of minimally invasive surgical approaches in periodontal surgery. Harrel & Rees proposed the minimally invasive surgery (MIS) with the aim to produce minimal wounds, minimal flap reflection and gentle hand ling of the soft ...

Phase N/A

Effects of Scaling and Root Planing With and Without Er:YAG Laser in Chronic Periodontitis Patients

Primary Aim: The primary aim of this study is to evaluate the efficacy of Er:YAG laser as an adjunct to mechanical scaling and root planing periodontal therapy by comparing probing depth and clinical attachment levels. Secondary aim: The secondary aim of this study is to evaluate the efficacy of Er:YAG ...

Phase N/A

Essential Oils With and Without Alcohol: Substantivity and Antiplaque Effect

The Essential oils (EO) are composed by a wide diversity of products. Therefore, their antimicrobial activity will be related to their composition, configuration, amount and their possible interaction. The traditional formulation containing EO (T-EO) is a complex mixture of phenolic compounds combined with determinate EO: 0.092% of eucalyptol, 0.064% of ...

Phase

Immunoregulation of Periodontal Diseases

Periodontal diseases are a group of diseases that affect 15% of the population and in the absence of treatment causes tooth loss. Periodontal lesions are characterized mainly by strong inflammation and hyper-vascularization. Search in blood cells and inflammatory markers attempts to explain the etiological-pathogenetic mechanisms. Innate immunity can be assessed ...

Phase N/A

Periodontal Impact of Eating Disorders (the PERIOED Study)

Eating disorders have been associated with poor oral health. However, the relationship between eating disorders and periodontal diseases is less-established. Participants will be periodontally assessed using a full-mouth clinical evaluation.

Phase N/A

FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis

In a randomize, prospective study 200 patients from the endocrinology department of "Peja's Regional Hospital" and Dental Polyclinic at city of Peja, will be assessed and examined for eligibility. Personal interviews will be used to collect the baseline data from each participant using a pre structured questionnaire. After clinical examination, ...

Phase N/A

Impact of Debridement Invasiveness on Attachment Gain After Antiinfective Periodontal Therapy

The concomitant removal of subgingival calculus and soft bacterial biofilms in a one-stage procedure might impair periodontal healing in deep infrabony pockets due to the mechanical disruption of demineralized bone sections at the bottom of periodontal lesions. This randomized controlled clinical trial therefore aims at comparing the resulting attachment gain ...

Phase N/A

Vitamin C as an Adjunct in Periodontal Treatment in Type 2 Diabetes Mellitus Patients

Periodontitis patients with uncontrolled type 2 diabetes mellitus will receive non-surgical periodontal treatment and then be supplemented with daily 500 mg vitamin C (test group) or placebo (control group) for 2 months. Clinical parameters will be retrieved at baseline, at the end of week 4 and at the end of ...

Phase