Brain Tumor Clinical Trials

A listing of Brain Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 169 clinical trials
Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis

The investigators will develop the concept of a sex-specific therapeutic intervention for gliomas that is based upon dietary carbohydrate restriction. The investigators will integrate metabolomics tools and FDG-PET imaging to validate the ketogenic diet on a sex-specific basis.

  • 7 views
  • 04 Oct, 2022
  • 1 location
Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioblastoma is a highly aggressive and fatal form of primary malignant brain tumor with limited treatment options. fb-PMT affects a large group of cancer cell signaling pathways and thus may be

karnofsky performance status
recurrent glioblastoma
brain tumor
cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
Randomized Control Trial for Awake vs. Asleep Craniotomy for Non-eloquent Gliomas

This study protocol examines a comparison between local and general anesthesia (Awake vs. Asleep Craniotomy) in the removal of brain tumors that are in areas of the brain that do not directly

  • 0 views
  • 23 Oct, 2022
  • 1 location
Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

the Preston Robert Tisch Brain Tumor Center (PRTBTC) at Duke.

recurrent malignant glioma
malignant glioma
brain tumor
  • 0 views
  • 04 Oct, 2022
  • 1 location
Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

microdialysis catheter) to recover an expanded range of potential biomarkers from the diseased human central nervous system in the context of surgery for brain tumors. This study is performed under an

  • 0 views
  • 04 Oct, 2022
  • 1 location
Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-methylated Glioblastoma: a Randomized Phase II Open Label Multicenter Study (RIGOLETTO)

Romiplostim for low platelets caused by lomustine chemotherapy in patients with first recurrence (growing back) of a brain tumor, glioblastoma that is MGMT methylated. Lomustine is an

  • 0 views
  • 17 Oct, 2022
  • 1 location
A Dose Escalation and Expansion Study of Sonodynamic Therapy With SONALA-001 in Combination With Exablate 4000 Type-2 MR-guided Focused Ultrasound in Patients With Recurrent or Progressive Glioblastoma Multiforme

The primary objectives of this trial are to evaluate the safety, dose-limiting toxicities, recommended Phase 2 schedule, and preliminary efficacy of sonodynamic therapy (SDT) using SONALA-001 and Exablate Type-2 device in subjects with recurrent or progressive GBM.

  • 0 views
  • 22 Oct, 2022
  • 1 location
Cancer Genetic Testing in Ethnic Populations

This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these …

nervous
cancer
  • 0 views
  • 07 Oct, 2022
  • 2 locations
An Open Label, Multi-center Roll-over Study to Assess Long-term Effect in Pediatric Patients Treated With Tafinlar (Dabrafenib) and/or Mekinist (Trametinib)

A roll-over study to assess long-term effect in pediatric patients treated with dabrafenib and/or trametinib.

trametinib
dabrafenib
  • 492 views
  • 29 Oct, 2022
  • 15 locations
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (SPARTA)

The primary Phase 1 purpose of this study was to assess overall safety, tolerability and recommended Phase 2 dose (RP2D) of APL-101. The Phase 2 portion will assess efficacy of the dose determined in Phase 1 in individuals with Non-Small Cell Lung Cancer with c-Met EXON 14 Skip Mutations; individuals …

solid neoplasm
epidermal growth factor
solid tumors
epidermal growth factor receptor
solid tumour
  • 326 views
  • 04 Oct, 2022
  • 85 locations