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Narcolepsy Clinical Trials

A listing of Narcolepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (21) clinical trials

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

Phase

Do you or a loved one have narcolepsy, coupled with loss of muscle control when experiencing strong emotions (cataplexy)? Are you interested in taking part in a medication research study for this condition?   Wake Research is seeking individuals with narcolepsy to take part in a research study of an ...

Phase N/A

This study is double-blind and placebo controlled and intended to assess the efficacy and safety of a once nightly formulation of sodium oxybate for extended-release oral suspension (FT218) for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy. This study will be 14-17 weeks long and requires ...

Phase N/A

This is an 18-week, double-blind, placebo-controlled study to evaluate the efficacy of JZP-258 in the treatment of cataplexy and excessive daytime sleepiness in subjects with narcolepsy. This study also has an optional 24-week open label extension period. 

Phase N/A

The purpose of this study is to determine whether Sodium Oxybate is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.  

Phase

The CONCERT (Clinical Outcomes in Narcolepsy and Cataplexy: An Evaluation of Reboxetine Treatment) study is being conducted to determine how safe and how well an investigational drug works for patients with excessive daytime sleepiness and cataplexy in narcolepsy. Eligible participants will receive study-related care at no cost.

Phase

Xyrem and Brain Dopamine in Narcolepsy

The overall aim of this investigation is to establish whether an action of Xyrem on the brain dopamine system in patients with narcolepsy, and in a comparison control group, might explain part of the anti-narcoleptic effect of the drug. Trial Objective is to establish, using positron emission tomography (PET), in ...

Phase

Study Assessing Effects of JZP-110 on Driving Performance in the Treatment of Excessive Sleepiness in Narcolepsy

This trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to narcolepsy.

Phase

Exploration of the Reward System by Functional MRI in Narco-cataplexy Patients With and Without REM Sleep Behavior Disorder

Type of study: Prospective, case control study. Number of centers: 3 (Clermont-Ferrand, Vichy and Montlucon) Patients : The study will be performed in 66 subjects (22 PD patients with RBD, 22 PD patients without RBD and 22 healthy volunteers, age-and sex-matched without any contraindications to perform an MRI) Study Performance ...

Phase N/A

Investigation of Clinical Feature and Brain Function in Narcoleptic Patients

Polysomnographic (PSG) work-up one night to record nocturnal sleep condition in narcolepsy with /without RBD and control subjects including sleep macrostructure, occurrence of sleep onset rapid eye movement period(SOREMP), sleep stages distribution, and sleep arousle and leg movement and apnea hyponea index would be calculated. Functional magnetic resonance imaging (fMRI) ...

Phase N/A