Narcolepsy Clinical Trials

The purpose of this study is to determine whether FT218 is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.

This is a 6-week crossover, placebo-controlled study to assess the safety and efficacy of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness. Subjects who meet criteria will be randomized in a 1:1 ratio either to placebo for 3 weeks followed by AXS-12 (up to 10mg daily) for 3 ...

The purpose of this study is to determine whether Sodium Oxybate is safe and effective for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy.  

This study is of an investigational drug called SUVN-G3031 as a possible treatment for narcolepsy with cataplexy or narcolepsy without cataplexy. The main purpose of this study is to learn how well the study drug works and how safe the study drug is compared to placebo.  

To evaluate the safety and efficacy of IPX203 (carbidopa and levodopa) extended-release capsules (IPX203 ER CD-LD) in comparison to immediate release (IR) CD-LD in the treatment of CD-LD-experienced subjects with Parkinson's disease (PD) who have motor fluctuations.  

Do you or a loved one have narcolepsy, coupled with loss of muscle control when experiencing strong emotions (cataplexy)? Are you interested in taking part in a medication research study for this condition?   Wake Research is seeking individuals with narcolepsy to take part in a research study of an ...

This study is double-blind and placebo controlled and intended to assess the efficacy and safety of a once nightly formulation of sodium oxybate for extended-release oral suspension (FT218) for the treatment of excessive daytime sleepiness and cataplexy in subjects with narcolepsy. This study will be 14-17 weeks long and requires ...

This trial is a randomized, double-blind, placebo-controlled, crossover study to evaluate the effect of JZP-110 on driving performance in subjects with excessive sleepiness due to narcolepsy.

Type of study: Prospective, case control study. Number of centers: 3 (Clermont-Ferrand, Vichy and Montlucon) Patients : The study will be performed in 66 subjects (22 PD patients with RBD, 22 PD patients without RBD and 22 healthy volunteers, age-and sex-matched without any contraindications to perform an MRI) Study Performance ...

Polysomnographic (PSG) work-up one night to record nocturnal sleep condition in narcolepsy with /without RBD and control subjects including sleep macrostructure, occurrence of sleep onset rapid eye movement period(SOREMP), sleep stages distribution, and sleep arousle and leg movement and apnea hyponea index would be calculated. Functional magnetic resonance imaging (fMRI) ...