Primary Immunodeficiency Disorders Clinical Trials

A listing of Primary Immunodeficiency Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 674 clinical trials
A Washington University research study is currently enrolling participants with diagnosed primary immunodeficiency disorder (PID).

The purpose of the research study is to find out if the COVID – 19 vaccine can produce an immune response in patients with PID. The study will also look at genetic factors that determine response. 

  • 11 May, 2021
  • 1 location
A Washington University research study is currently enrolling participants with primary Immune deficiency (PID). IRB ID #: 201910008

The purpose of this research study is to investigate different ways to dose with CUTAQUIG ® in patients suffering from primary Immune deficiency (PID).

immune deficiency
immune disorder
primary immunodeficiency disorders
primary immunodeficiency
  • 25 Jan, 2021
  • 1 location
COVID-19 Vaccination of Immunodeficient Persons (COVAXID)

The study is designed as an open, non-randomized, phase IV cohort study in which the mRNA vaccine Comirnaty will be given in two doses. Analyses will be performed on blood and saliva, investigating humoral and cellular vaccine responses. Occurence of local or systemic reactogenicity will be evaluated, as well as …

  • 15 Mar, 2021
  • 1 location
Study to Evaluate Safety and Pharmacokinetics of BIVIGAM in Primary Immune Deficiency Subjects Aged 2 to 16

This study is part of the BIVIGAM post marketing requirement (PMR). It is being conducted in subjects aged 2-16 with primary immune deficiency disorders associated with defects in humoral

  • 23 Jun, 2021
  • 9 locations
Efficacy and Safety of Romiplostim Versus Eltrombopag in the Treatment of Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome

This is a prospective, open-label, randomized, two-arm clinical trial conducted to evaluate the safety and efficacy of romiplostim in comparison with eltrombopag in the treatment of thrombocytopenia in patients with Wiskott-Aldrich syndrome

  • 24 Jan, 2021
  • 1 location
N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)

This is a multinational, multicenter, open-label, rater-blinded prospective Phase II study which will assess the safety and efficacy of N-Acetyl-L-Leucine (IB1001) for the treatment of Ataxia-Telangiectasia (A-T). There are two phases to this study: the Parent Study, and the Extension Phase. The Parent Study evaluates the safety and efficacy of …

  • 18 Apr, 2021
  • 5 locations
A Dose-Range Finding Clinical Trial Study in Human Immunodeficiency Virus (HIV-1) Infected Treatment-Naive Adults

This is a phase 2b, randomized, multicenter, parallel group, partially blind (to GSK3640254 doses [100, 150 and 200 milligrams {mg}]), active controlled clinical trial. It will aim to investigate the safety, efficacy and dose-response of GSK3640254 compared to dolutegravir (DTG), each given in combination with 2 Nucleoside Reverse Transcriptase Inhibitors …

hiv-1 rna measurement
  • 14 Jul, 2021
  • 50 locations
Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study

The purpose of this study is to learn whether having the AMP Study antibody (called VRC01) in a person's body might help their immune system control HIV better, even without HIV medication called antiretroviral therapy or ART, if they get HIV. This study will evaluate the viral and immune system …

antiretroviral therapy
hiv test
hiv-1 rna measurement
HIV Vaccine
  • 31 Jul, 2021
  • 11 locations
Viral Load Triggered ART Care in Lesotho

This cluster randomized clinical trial at 18 nurse-led rural health centers in Lesotho will test an automated differentiated service delivery model using viral load results, other clinical characteristics and participants' preference to automatically triage participants into groups requiring different levels of attention and care.

antiretroviral agents
antiretroviral therapy
  • 07 Jun, 2021
  • 14 locations
A Study Evaluating Implementation Strategies for Cabotegravir (CAB)+ Rilpivirine (RPV) Long-acting (LA) Injectables for Human Immunodeficiency Virus (HIV)-1 Treatment in European Countries

The overall objective of the CAB LA + RPV LA clinical development program is to develop a highly effective, well-tolerated, two-drug, LA injectable regimen which has the potential to offer improved treatment convenience, compliance and improved quality of life for people living with HIV compared to current standard of care. …

hiv-1 rna measurement
HIV Vaccine
antiretroviral therapy
  • 08 Jul, 2021
  • 15 locations