Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1021 clinical trials
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to

ifosfamide
tumor cells
etoposide
immature teratoma
platelet count
  • 0 views
  • 20 Jul, 2022
  • 32 locations
Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

This phase II trial studies how well nivolumab and relatlimab work in treating participants with chordoma that has spread to other places in the body. Monoclonal antibodies, such as nivolumab and relatlimab, may interfere with the ability of tumor cells to grow and spread.

monoclonal antibodies
metastasis
tumor cells
cancer
gilbert's disease
  • 12 views
  • 15 May, 2022
  • 1 location
Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT) (TANGENT)

This is a multicenter, Phase 3, randomised, double-blind, placebo-controlled study, which aims to evaluate the efficacy and safety of the investigational drug emactuzumab for the treatment of patients with localized or diffuse TGCT where surgical removal of the tumor is not viewed as an option. The study consists of two …

  • 0 views
  • 11 Aug, 2022
Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

children undergoing radiotherapy for localized brain tumors (low grade glioma, craniopharyngioma, ependymoma, or germ cell tumor) To estimate the rate of memantine medication adherence

mg++
low grade glioma
memantine
ganglioglioma
dementia
  • 34 views
  • 12 May, 2022
  • 1 location
A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects (OPTIMUM)

The purpose of this study is to evaluate the efficacy and safety of 131I-MIBG in combination with Vorinostat in patients with Recurrent or Progressive neuroblastoma

iobenguane
ifosfamide
etoposide
avid
topotecan
  • 58 views
  • 24 Mar, 2022
  • 16 locations
C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

This study is for patients with high grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG) or medulloblastoma or another rare brain cancer that expresses GD2. Because there is no standard treatment at this time, patients are being asked to volunteer in a gene transfer research study using special immune …

dexamethasone
tumor cells
malignant glioma
platelet count
brain tumor
  • 1 views
  • 11 Mar, 2022
  • 1 location
  • 0 views
  • 01 Jul, 2022
  • 1 location
Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma

This is a multicenter, single arm, phase 2 study designed to evaluate the efficacy and safety of cetuximab for the treatment of advanced (unresectable)/metastatic, chordoma. The target patient population will be any chordoma patient 18 years of age with locally unresectable disease or metastatic disease.

renal function
gilbert's disease
measurable disease
absolute neutrophil count
metastatic chordoma
  • 0 views
  • 18 Jun, 2022
  • 1 location
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-na ve GBM Patients.

A multi-center, open-label, single-arm, phase I/II clinical study is designed to test the safety and immunogenicity of an investigational Dendritic and Glioma Cells Fusion vaccine given with IL-12 for treatment-nave patients after resection of glioblastoma.

mg++
cancer chemotherapy
ejection fraction
tumor cells
temozolomide
  • 57 views
  • 24 Jan, 2021
  • 2 locations
Olanzapine Combined With Fosaprepitant, Ondansetron, and Dexamethasone for Preventing Nausea and Vomiting in Patients With Testicular Cancer

dexamethasone in the prevention of nausea and vomiting in germ-cell tumors receiving 5-day cisplatin chemotherapy

  • 0 views
  • 26 Mar, 2022
  • 1 location