Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1020 clinical trials
A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

The purpose of the CTO-IUSCCC-0752 study is to investigate the use of Cabozantinib for patients with incurable, refractory germ cell tumors. Patients will be treated until evidence of disease

human chorionic gonadotropin
mg++
tumor markers
cancer chemotherapy
alpha fetoprotein
  • 0 views
  • 10 Jun, 2021
  • 1 location
Reduced Dose Radiotherapy Following High Dose Chemotherapy in Intracranial Non-germinomatous Germ Cell Tumor

The purpose of this study is to evaluate the outcome of intracranial non-germinomatous germ cell tumor (NGGCT) treated with reduced radiotherapy following high dose chemotherapy and autologous

  • 1 views
  • 25 Jan, 2021
  • 1 location
TC or BEP in Treating Patients With Malignant Ovarian Germ Cell Tumors

newly diagnosed malignant ovarian germ cell tumor patients after surgery.

cytoreduction
carboplatin
germ cell tumor
paclitaxel
etoposide
  • 13 views
  • 25 Jan, 2021
  • 1 location
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to

stem cell transplantation
tumor markers
alpha fetoprotein
beta-human chorionic gonadotropin
carcinoma
  • 0 views
  • 01 Sep, 2021
  • 4 locations
Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

This phase II trial studies how well nivolumab and relatlimab work in treating participants with chordoma that has spread to other places in the body. Monoclonal antibodies, such as nivolumab and relatlimab, may interfere with the ability of tumor cells to grow and spread.

human chorionic gonadotropin
relatlimab
ct scan
monoclonal antibodies
nivolumab
  • 10 views
  • 28 Aug, 2021
  • 1 location
Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

children undergoing radiotherapy for localized brain tumors (low grade glioma, craniopharyngioma, ependymoma, or germ cell tumor) To estimate the rate of memantine medication adherence

brain tumor
ganglioglioma
low grade glioma
human chorionic gonadotropin
memantine
  • 28 views
  • 16 Apr, 2021
  • 1 location
A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjects

The purpose of this study is to evaluate the efficacy and safety of 131I-MIBG in combination with Vorinostat in patients with Recurrent or Progressive neuroblastoma

total bilirubin
growth factor
karnofsky performance status
avid
platelet transfusion
  • 58 views
  • 10 Jun, 2021
  • 15 locations
Anlotinib Hydrochloride Versus Imatinib Mesylate in Locally Advanced Unresectable or Metastatic Chordoma

For local relapse not amenable to reasonable curative surgery or for those with metastatic chordoma, chemotherapy is recognised as inactive. The major study drug is the small molecular tyrosine kinase inhibitors targeted at the stem cell factor receptor (KIT) and the platelet-derived growth factor receptors (PDGFRA and PDGFRB), eg. imatinib. …

tyrosine
sarcoma
ct scan
PDGFRA
imatinib
  • 2 views
  • 23 Jan, 2021
  • 1 location
C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

This study is for patients with high grade glioma (HGG) or diffuse intrinsic pontine glioma (DIPG) or medulloblastoma or another rare brain cancer that expresses GD2. Because there is no standard treatment at this time, patients are being asked to volunteer in a gene transfer research study using special immune …

brain tumor
measurable disease
diffuse intrinsic pontine glioma
cyclophosphamide
malignant glioma
  • 1 views
  • 11 Apr, 2021
  • 1 location
Living After a Rare Cancer of the Ovary: Chronic Fatigue Quality of Life and Late Effects of Chemotherapy

While they are documented in patients in remission of testicular cancer, the sequelae of chemotherapy and the impact of the disease and its treatments on the living conditions and QoL of women in remission of rare ovarian cancer remain poorly explored. The coordinator therefore propose a national 2-step case-control study …

testicular
carcinoma
cancer
cancer chemotherapy
  • 18 views
  • 26 Jul, 2021
  • 29 locations