Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 998 clinical trials
TC or BEP in Treating Patients With Malignant Ovarian Germ Cell Tumors (MOGCT-01)

newly diagnosed malignant ovarian germ cell tumor patients after surgery.

carboplatin
carboplatin/paclitaxel
paclitaxel
cytoreduction
germ cell tumor
  • 24 views
  • 13 Feb, 2022
  • 1 location
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

) embryonal tumors completing "Head Start 4" Induction. This study will further determine whether the additional labor intensity (duration of hospitalizations and short-term and long-term morbidities

corticosteroids
glomerular filtration rate
MRI
medulloblastoma
platelet count
  • 197 views
  • 23 Mar, 2022
  • 61 locations
The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors

Primary endpoint three-year disease-free survival of patients with localized basal ganglia germ cell tumors receiving whole-ventricle irradiation Health-related quality

  • 0 views
  • 25 Nov, 2021
  • 1 location
Reduced Dose Radiotherapy Following High Dose Chemotherapy in Intracranial Non-germinomatous Germ Cell Tumor

The purpose of this study is to evaluate the outcome of intracranial non-germinomatous germ cell tumor (NGGCT) treated with reduced radiotherapy following high dose chemotherapy and autologous

  • 1 views
  • 25 Jan, 2021
  • 1 location
Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).

tumor markers
human chorionic gonadotropin
hysterectomy
ifosfamide
high-dose chemotherapy
  • 0 views
  • 08 Mar, 2022
  • 1 location
A Phase II Trial of Cabozantinib With Patients With Refractory GCTs

The purpose of the CTO-IUSCCC-0752 study is to investigate the use of Cabozantinib for patients with incurable, refractory germ cell tumors. Patients will be treated until evidence of disease

tumor markers
human chorionic gonadotropin
beta-human chorionic gonadotropin
platelet count
cancer chemotherapy
  • 1 views
  • 08 Jul, 2022
  • 1 location
Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours

The purpose of this study is to determine whether accelerated BEP chemotherapy is more effective than standard BEP chemotherapy in males with intermediate and poor-risk metastatic germ cell tumours.

g-csf
human chorionic gonadotropin
testicular
metastasis
platelet count
  • 80 views
  • 07 Dec, 2021
  • 28 locations
Disulfiram and Cisplatin in Refractory TGCTs. (DISGCT)

/refractory germ cell tumors (GCTs).

germ cell cancer
measurable disease
human chorionic gonadotropin
major surgery
high-dose chemotherapy
  • 15 views
  • 08 Feb, 2022
  • 1 location
CDK4/6 Inhibition in Locally Advanced/Metastatic Chordoma

In chordoma cell lines and patient biopsies, the p16 (CDKN2A) tumor suppressor is consistently deleted. Thus, chordomas are an example of a tumor with universal activation of the cyclin-dependent kinases 4 and 6 (CDK4/6) pathway, and experiments with patient-derived chordoma cell lines demonstrate aberrant CDK4/6 activity downstream of p16 loss …

metastatic chordoma
hysterectomy
imatinib
vasectomy
cancer chemotherapy
  • 39 views
  • 07 Jan, 2022
  • 3 locations
A Phase 2 Trial of Chemotherapy Followed by Response-Based Whole Ventricular &Amp; Spinal Canal Irradiation (WVSCI) for Patients With Localized Non-Germinomatous Central Nervous System Germ Cell Tumor

cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to

carboplatin
human chorionic gonadotropin
mesna
immature teratoma
neutrophil count
  • 0 views
  • 19 Aug, 2022
  • 35 locations