Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1052 clinical trials
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Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients

Progastrin is a pro-hormone that, in physiological conditions, is maturated in gastrin in G cells of the stomach. The role of the gastrin is to stimulate the secretion of gastric acids during digestion. It is also important for the regulation of cell growth of the gastric mucosal. In a healthy …

uterine disease
cancer treatment
breast ductal carcinoma
hormone therapy
nephrectomy
  • 0 views
  • 25 Jul, 2021
  • 10 locations
None
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors Lymphomas or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

cancer treatment
fgfr inhibitor
afatinib
measurable disease
lhrh
  • 6118 views
  • 01 Dec, 2021
  • 1030 locations
None
A Study of XmAb 20717 in Subjects With Selected Advanced Solid Tumors

This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity of XmAb20717 in subjects with selected advanced solid tumors.

erbb2
measurable disease
formalin-fixed paraffin-embedded
solid tumour
adenoid cystic carcinoma
  • 417 views
  • 10 May, 2021
  • 17 locations
None
PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors

A Phase 1 dose escalation and expansion study evaluating safety, tolerability and pharmacokinetics of PF-06952229 in adult patients with advanced solid tumors.

erbb2
measurable disease
hysterectomy
formalin-fixed paraffin-embedded
metastasis
  • 58 views
  • 29 Oct, 2021
  • 23 locations
None
Behavioral Weight Loss Program for Cancer Survivors in Maryland

Behavioral Weight Loss for Overweight and Obese Cancer Survivors in Maryland: A Demonstration Project

cancer
tamoxifen
breast cancer
  • 0 views
  • 20 Oct, 2021
  • 1 location
None
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

positron emission tomography
bladder cancer
thymus cancer
adrenaline
hematologic malignancy
  • 0 views
  • 23 Jul, 2021
  • 1 location
None
Evaluation of the Length of Treatment With PD-1/PD-L1 Inhibitors in Patients With Advanced Solid Tumors

Based on the overwhelming positive response to this survey and the large number of patients being treated with PD-1/PD-L1 therapy in the UPMC system, the investigators are proposing a trial that will randomize patients who have disease stability to stop treatment at 1 year or continue treatment until disease progression. …

solid tumor
measurable disease
atezolizumab
solid tumour
durvalumab
  • 15 views
  • 28 Jan, 2021
  • 1 location
None
A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a Phase 1b, open-label dose escalation trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally occurring human antibody. The safety, tolerability, PK, and biological activity of ATRC-101 will be characterized when administered every two weeks (Q2W) or every 3 weeks …

ovarian cancer
platelet count
cancer treatment
chemotherapy regimen
measurable disease
  • 4 views
  • 12 Nov, 2021
  • 13 locations
None
Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

This is a first-in-human, Phase 1, open label, multicenter, multiple dose, dose escalation and expansion study intended to evaluate the safety, viral load kinetics and shedding, pharmacodynamic, and anti-tumor activity of PF-07263689, either alone or in combination with sasanlimab (an investigational anti-programmed cell death protein 1 [PD-1] antibody), in patients …

programmed cell death 1 ligand 1
monoclonal antibodies
combination therapy
measurable disease
growth factor
  • 0 views
  • 14 Nov, 2021
  • 1 location
None
Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Earlier detection of disease recurrence will enable greater treatment options and has strong potential to improve patient outcomes. This project is translational and has the potential to lead to future translational research opportunities, including interventional trials in which therapeutic escalation is offered at the early circulating tumor DNA (ctDNA) molecular …

precision medicine
residual disease
cancer diagnosis
solid tumor
cancer
  • 0 views
  • 11 Apr, 2021
  • 1 location