Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1020 clinical trials
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)

This is a randomized open-label multicentre Phase III superiority study of the effect of adding SBRT to the standard of care treatment on overall survival in patients with rare oligometastatic cancers. Patients will be randomized in a 1:1 ratio between current standard of care treatment vs. standard of care treatment …

metastasis
brain metastases
systemic therapy
  • 0 views
  • 09 Jul, 2021
  • 3 locations
Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers

This exploratory study investigates how an imaging technique called 68Ga-FAPi-46 PET/CT can determine where and to which degree the FAPI tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues in patients with cancer. Because some cancers take up 68Ga-FAPi-46 it can be seen with PET. FAP stands for Fibroblast Activation Protein. …

hematologic malignancy
pet/ct scan
dotatate
ct scan
bladder tumor
  • 0 views
  • 23 Jul, 2021
  • 1 location
MRx0518 in Patients With Solid Tumours Waiting Surgical Removal of the Tumour

The primary objective is to determine the safety and tolerability of the novel compound, MRx0518 in patients with solid tumours at 30 days post-surgery. 20 participants will receive open label MRx0518 in a preliminary safety phase. After successful evaluation by the Independent Safety Monitoring Committee (IDMC), a further 100 participants …

cancer
cancer chemotherapy
  • 13 views
  • 23 Jan, 2021
  • 1 location
Study of NGM120 in Subjects With Advanced Solid Tumors and Pancreatic Cancer Using Combination Therapy

Study of NGM120 in subjects with advanced solid tumors and pancreatic cancer.

gastric cancer
adenocarcinoma
immunostimulant
immunomodulator
lung carcinoma
  • 139 views
  • 31 May, 2021
  • 23 locations
PF-06952229 Treatment in Adult Patients With Advanced Solid Tumors

A Phase 1 dose escalation and expansion study evaluating safety, tolerability and pharmacokinetics of PF-06952229 in adult patients with advanced solid tumors.

spiral computed tomography
adenocarcinoma
neutrophil count
formalin-fixed paraffin-embedded
carcinoma
  • 58 views
  • 21 Sep, 2021
  • 23 locations
Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors for Immunotherapy of Advanced Solid Tumors

This trial was designed to investigate the safety, response rates and survival outcomes of patients with advanced solid tumors by trans-artery/intra-tumor infusion of PD1/PDL1 antibody and/or CTLA4 antibody ipilimumab and to compare their differences.

cancer
total bilirubin
solid tumors
solid tumour
measurable disease
  • 25 views
  • 23 Jan, 2021
  • 1 location
A Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a Phase 1b, open-label dose escalation trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally occurring human antibody. The safety, tolerability, PK, and biological activity of ATRC-101 will be characterized when administered every two weeks (Q2W) or every 3 weeks …

mek inhibitor
neutrophil count
cancer treatment
pembrolizumab
BRAF
  • 4 views
  • 12 Jun, 2021
  • 13 locations
Oral TrkA Inhibitor VMD-928 for Treatment of Advanced Adult Solid Tumors or Lymphoma

This is a multicenter, open-label, Phase 1 study of orally administered VMD-928 in adult subjects with advanced solid tumors or lymphoma that have progressed or are non responsive to available therapies and for which no standard or available curative therapy exists

solid tumor
gastric cancer
thymic carcinoma
lymphoma
carcinoma
  • 31 views
  • 25 Mar, 2021
  • 5 locations
A Study of DSP-7888 Dosing Emulsion in Combination With Immune Checkpoint Inhibitors in Adult Patients With Advanced Solid Tumors

This is a Phase 1b/2, open-label, multicenter study of DSP-7888 Dosing Emulsion in combination with checkpoint inhibitors (nivolumab or pembrolizumab) in adult patients with solid tumors, that consists of 2 parts: dose search part of the study (Phase 1b and Phase 1b Enrichment Cohort) and the dose expansion part of …

immunostimulant
blood transfusion
neutrophil count
fallopian tube
metastatic urothelial carcinoma
  • 59 views
  • 15 Sep, 2021
  • 25 locations
Evaluation of the Length of Treatment With PD-1/PD-L1 Inhibitors in Patients With Advanced Solid Tumors

Based on the overwhelming positive response to this survey and the large number of patients being treated with PD-1/PD-L1 therapy in the UPMC system, the investigators are proposing a trial that will randomize patients who have disease stability to stop treatment at 1 year or continue treatment until disease progression. …

solid tumor
durvalumab
pd-l1
atezolizumab
nivolumab
  • 15 views
  • 28 Jan, 2021
  • 1 location