Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 165 clinical trials
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active

cancer chemotherapy
carboplatin
mg++
testicular
carcinoma
  • 341 views
  • 30 Jul, 2021
  • 369 locations
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide

cancer chemotherapy
carboplatin
testicular
seminoma
cancer
  • 803 views
  • 31 Jul, 2021
  • 96 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphomas or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

gliomas
absolute neutrophil count
cancer
total body irradiation
stem cell transplantation
  • 997 views
  • 01 Aug, 2021
  • 114 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

mucinous adenocarcinoma Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) Trophoblastic tumor: A

extramammary paget's disease
teratoma with malignant transformation
chordoma
systemic therapy
peritoneal mesothelioma
  • 6047 views
  • 01 Aug, 2021
  • 815 locations
Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma

This phase II trial studies how well nivolumab and relatlimab work in treating participants with chordoma that has spread to other places in the body. Monoclonal antibodies, such as nivolumab and relatlimab, may interfere with the ability of tumor cells to grow and spread.

gonadotropin
platelet count
absolute neutrophil count
metastasis
cancer
  • 10 views
  • 18 Jul, 2021
  • 1 location
Living After a Rare Cancer of the Ovary: Chronic Fatigue Quality of Life and Late Effects of Chemotherapy

While they are documented in patients in remission of testicular cancer, the sequelae of chemotherapy and the impact of the disease and its treatments on the living conditions and QoL of women in remission of rare ovarian cancer remain poorly explored. The coordinator therefore propose a national 2-step case-control study …

cancer chemotherapy
testicular
carcinoma
cancer
  • 18 views
  • 26 Jul, 2021
  • 29 locations
A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients

The purpose of this Phase 2, open-label, multiple-dose, dose-escalation study is to evaluate intravenous AMB-05X in the treatment of patients with TGCT.

  • 0 views
  • 18 Jul, 2021
  • 5 locations
Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well samotolisib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with TSC or PI3K/MTOR mutations that have spread to other places in the body (metastatic) and have come back (recurrent) or do not respond to treatment (refractory). Samotolisib …

cancer
total body irradiation
stem cell transplantation
platelet transfusion
anticonvulsants
  • 377 views
  • 01 Aug, 2021
  • 85 locations
Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well larotrectinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with NTRK fusions that have spread to other places in the body and have come back or do not respond to treatment. Larotrectinib may stop the growth of …

nervous system disorders
cancer
brain metastasis
total body irradiation
cancer treatment
  • 351 views
  • 01 Aug, 2021
  • 84 locations
Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

This phase II Pediatric MATCH trial studies how well palbociclib works in treating patients with Rb positive solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with activating alterations (mutations) in cell cycle genes that have spread to other places in the body and have come back or do not respond to …

cancer
total body irradiation
cancer treatment
stem cell transplantation
platelet transfusion
  • 91 views
  • 01 Aug, 2021
  • 81 locations