Germ Cell Tumors Clinical Trials

A listing of Germ Cell Tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 1009 clinical trials
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ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

ACNS1123: Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT)

  • 176 views
  • 08 Nov, 2020
  • 1 location
Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease (SACRO)

Comparative study on surgery versus definitive radiation therapy in primary localized sacral chordoma

proton therapy
antineoplastic
ct scan
  • 71 views
  • 25 Feb, 2022
  • 12 locations
Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

This phase III trial studies how well active surveillance, bleomycin, etoposide, carboplatin or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance

beta-human chorionic gonadotropin
platelet count
carboplatin
testicular
teratoma
  • 596 views
  • 14 Apr, 2022
  • 342 locations
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors

germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, cisplatin, carboplatin, and etoposide

ifosfamide
g-csf
platelet count
alpha fetoprotein
carboplatin
  • 907 views
  • 03 May, 2022
  • 103 locations
A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.

program. METHOD: PASCA is a single-center, interventional cohort study of adult patients who received at least chemotherapy and with a complete remission to a testicular germ cell tumor, primary

  • 0 views
  • 16 Feb, 2021
  • 1 location
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) (AcceleRET-Lung)

This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcomes when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for …

cancer treatment
pralsetinib
metastatic non-small cell lung cancer
chemoradiotherapy
carboplatin
  • 34 views
  • 01 May, 2022
  • 77 locations
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists …

ascites
hodgkin's disease
platelet count
ulixertinib
ensartinib
  • 1029 views
  • 13 May, 2022
  • 103 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

mucinous adenocarcinoma Non-epithelial tumors of the ovary: A) Germ cell tumor of ovary B) Mullerian mixed tumor and adenosarcoma (closed to accrual 03/30/2018) Trophoblastic tumor: A

estimated creatinine clearance
carcinoid
gonadotrophin releasing hormone
pd-l1
pheochromocytoma, malignant
  • 6607 views
  • 11 May, 2022
  • 767 locations
Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT

This is an open label randomized phase II trial of maintenance oral etoposide vs. observation in patinets with relapsed GCT treated with high-dose chemotherapy (HDCT) and peripheral-blood stem-cell transplant (PBSCT).

ifosfamide
neutrophil count
alpha fetoprotein
hysterectomy
high-dose chemotherapy
  • 0 views
  • 08 Mar, 2022
  • 1 location
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors

) embryonal tumors completing "Head Start 4" Induction. This study will further determine whether the additional labor intensity (duration of hospitalizations and short-term and long-term morbidities

neutrophil count
central nervous system tumor
blood transfusion
platelet count
corticosteroids
  • 197 views
  • 23 Mar, 2022
  • 61 locations