Urothelial Tract Cancer Clinical Trials

A listing of Urothelial Tract Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 51 clinical trials
Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma

Due to discontinuation of the Codman C3000 pump, an alternate device is necessary to continue serving patients in need of hepatic arterial infusion chemotherapy. This study aims to test the safety of hepatic artery infusion pump placement, a standard surgical procedure, and intraarterial chemotherapy initiation with the standard medication floxuridine …

adenocarcinoma
floxuridine
metastatic adenocarcinoma
dexamethasone
colorectal adenocarcinoma
  • 0 views
  • 04 Jul, 2021
  • 1 location
Neoadjuvant Gemcitabine Plus Cisplatin With or Without Durvalumab in Resectable Biliary Tract Cancer

Considering that the poor prognosis of resected biliary tract cancer and negative impact on the survival outcomes of R1/R2 resection, neoadjuvant chemotherapy may improve R0 resection rates and the survival outcomes of patients with resectable biliary tract cancer. The addition of durvalumab to gemcitabine/cisplatin as neoadjuvant chemotherapy may improve the …

adenocarcinoma
biliary tract cancer
pet scan
cisplatin/gemcitabine
carcinoma
  • 1 views
  • 02 Aug, 2021
  • 1 location
LAMS Choledochoduodenostomies: With or Without Coaxial Plastic Stent

The aim of the study is to evaluate technical, clinical and safety outcomes of lumen-apposing metal stent (LAMS) with and without a coaxial double-pigtail plastic stent (DPS) in EUS-guided choledochoduodenostomies (CDS) for the management of biliary obstruction.

  • 1 views
  • 27 Feb, 2021
  • 1 location
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone

The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone

  • 0 views
  • 01 Mar, 2021
  • 1 location
A Study of Patients Receiving High-Dose Rate Brachytherapy

Background One standard way of giving radiation is to combine external beam treatments with internal brachytherapy treatments, which involve short-range radiation therapy that gives a high dose of radiation directly to a cancer or to the area where cancer cells were removed. Brachytherapy is done by placing hollow implant device(s) …

ct scan
carcinoma
metastasis
cancer
x-rays
  • 47 views
  • 25 Jul, 2022
  • 1 location
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors (REGOMUNE)

Assessment of the efficacy and safety of Regorafenib and Avelumab in patients with advanced or metastatic solid tumors (ten cohorts), once the Recommanded Phase II Dose (RP2D) has been determined (phase I trial). Assessement of the efficacy and safety of a low-dose of regorafenib (80mg/day) with avelumab in patients with …

ROS1
vascular endothelial growth factor
cancer
measurable disease
lung cancer
  • 44 views
  • 04 Mar, 2022
  • 6 locations
PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) (PLATON)

PLATON (Platform for Analyzing Targetable Mutations) is a prospective, multicentre, observational cohort study with biobanking. In a first approach PLATON's pilot-study assesses genomic profiling in gastrointestinal cancer therapy and the frequencies of targetable mutations including Tumor Mutational Burden (TMB) and Microsatellite Instability Status (MSI), performing Next-generation deep sequencing (NGS) using …

adenocarcinoma
pancreatic ductal adenocarcinoma
breast ductal carcinoma
immunostimulants
carcinoma
  • 0 views
  • 14 Jun, 2022
  • 30 locations
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumors (AMPLIFY-201)

This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide [Amph-CpG-7909] plus a mixture of lipid-conjugated peptide-based antigens [Amph-Peptides]) as adjuvant treatment of minimal residual disease (MRD) in subjects with KRAS/neuroblastoma ras viral oncogene homolog (NRAS) mutated PDAC or other solid …

NRAS
cancer chemotherapy
KRAS
  • 12 views
  • 27 Jul, 2022
  • 8 locations
Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics

This a prospective real-world navigation study using tumor DNA sequencing technology to sequence genes of previously treated and refractory gastrointestinal tumors, which are generally considered to be highly heterogeneous and complex, to screen potential molecular targeted drugs for individualized treatment. This study may provide feasibility and response information, which will …

erbb2
carcinoma
cancer
gastric cancer
pancreatic cancers
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering

A clinical trial to assess the safety and efficacy of genetically-engineered, neoantigen-specific Tumor Infiltrating Lymphocytes (TIL) in which the intracellular immune checkpoint CISH has been inhibited using CRISPR gene editing for the treatment of Gastro-Intestinal (GI) Cancer.

immunoglobulin
laparoscopy
minor surgical procedures
cancer
measurable disease
  • 53 views
  • 30 Aug, 2021
  • 1 location