Urothelial Tract Cancer Clinical Trials

A listing of Urothelial Tract Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)

Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)

gallbladder carcinoma
advanced biliary tract carcinoma
cisplatin/gemcitabine
gemcitabine
cancer
  • 102 views
  • 09 Jun, 2021
  • 162 locations
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

The purpose of this study is to determine the safety and efficacy of combination therapy with pembrolizumab (MK-3475) and lenvatinib (E7080/MK-7902) in participants with triple negative breast cancer (TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic cancer. All participants will be enrolled …

fallopian tube
cytotoxic chemotherapy
biliary cancer
combined modality therapy
growth factor
  • 611 views
  • 21 Jun, 2021
  • 82 locations
A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

This research study is done to test the safety of the new drug selitrectinib in children and adults with cancer having a change in a particular gene (NTRK1, NTRK2 or NTRK3). The drug may treat cancer by interfering with the effect of the NTRK genes on cancer growth. The study …

solid tumor
experimental drug
cancer
brain metastases
renal function tests
  • 1310 views
  • 20 Jun, 2021
  • 79 locations
Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04)

The purpose of this research study is to determine the safety and efficacy of CPI-613 (devimistat) in the treatment of advanced biliary tract cancer when used in combination with standard of care chemotherapy (gemcitabine plus cisplatin) compared to gemcitabine plus cisplatin alone. This research study has two parts: In the …

biliary tract cancer
advanced biliary tract carcinoma
cisplatin/gemcitabine
measurable disease
gemcitabine
  • 0 views
  • 11 Jun, 2021
  • 7 locations
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid Tumor

This is a Phase 1/2 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide [Amph-CpG-7909] plus a mixture of lipid-conjugated peptide-based antigens [Amph-Peptides]) as adjuvant treatment of minimal residual disease (MRD) in subjects with KRAS/neuroblastoma ras viral oncogene homolog (NRAS) mutated PDAC or other solid …

NRAS
KRAS
cancer chemotherapy
  • 0 views
  • 21 Jun, 2021
  • 8 locations
A Study of Patients Receiving High-Dose Rate Brachytherapy

Background One standard way of giving radiation is to combine external beam treatments with internal brachytherapy treatments, which involve short-range radiation therapy that gives a high dose of radiation directly to a cancer or to the area where cancer cells were removed. Brachytherapy is done by placing hollow implant device(s) …

metastasis
treatment regimen
cancer
lung cancer
breast cancer
  • 47 views
  • 21 Jun, 2021
  • 1 location
CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

Phase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.

erbb2
HER2
cancer
breast cancer
primary cancer
  • 0 views
  • 07 Jun, 2021
  • 2 locations
Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)

Background Cancer Cachexia (CC) is a multi-factorial process characterized by progressive weight loss, muscle mass and fat tissue wasting, and adversely affecting their quality of life and survival in patients with advanced stage of cancer. Megestrol acetate (MA), which can help maintain body weight in advanced cancer patients, has not …

cancer
cancer chemotherapy
lung cancer
lung carcinoma
  • 0 views
  • 09 Jun, 2021
  • 1 location
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer

Background Recent advances in cancer research have led to new therapies to treat the disease. It is important to continue these advances and discover new ones. To do that, researchers need tissue samples from solid tumors. This study will collect such samples from people already scheduled to have a procedure …

solid tumor
cancer
white blood cell count
solid tumour
  • 18 views
  • 18 Jun, 2021
  • 1 location
Recurrence After Whipple's (RAW) Study: Investigating Recurrence Patterns After Pancreaticoduodenectomy for Pancreatic Ampullary or Distal Bile Duct Cancer

Pancreatic head malignancies are aggressive cancers that are often inoperable when they are diagnosed. In the ~20% of patients who are diagnosed when the disease is still operable, surgery is the only treatment that can provide a chance of cure. Unfortunately, up to 75% of patients undergoing surgery will have …

pdac
pancreatic ductal adenocarcinoma
pancreaticoduodenectomy
cancer chemotherapy
adenocarcinoma
  • 50 views
  • 21 Jun, 2021
  • 12 locations