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Organ Transplant Clinical Trials

A listing of Organ Transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (56) clinical trials

Observational Study of the Clinical Use of the OCS Heart

This is an observational study at two centers that will enroll minimum of 60 heart transplant recipients transplanted with donor heart preserved using the OCS Heart System. All consented subjects who receive OCS-preserved heart transplants will be approached for participation. The study will evaluate short and long-term effectiveness of the …

Phase N/A

Monitoring of Donor-specific Antibodies After Treatment With Immunoglobulins Plasmapheresis and Rituximab in Lung Transplantation

This is an observational study to monitor the treatment of donor-specific antibodies in lung transplant recipients with detection of donor-specific antibodies. All consented subjects will be approached for participation. The study will evaluate the effectiveness of the treatment protocol of donor-specific antibodies with Immunoglobulins or combined treatment with Immunoglobulins, Plasmapheresis …

Phase N/A

Treatment of Anemia With Intravenous Iron in Patients Listed for Orthotopic Liver Transplantation

The aim of this study is to investigate whether therapy with intravenous iron carboxymaltose in patients with iron deficiency anemia (IDA) listed for orthotopic liver transplantation (OLT) increases hemoglobin concentrations and reduces intraoperative transfusion of packed red blood cells (PRBCs). The investigators hypothesize that therapy with intravenous iron will increase …


Qualitative and Quantitative Evaluation of Vascular Flows of Radial Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI

Allotransplants of vascularized composite tissues are subject to chronic vascular rejection, which can lead to graft loss. Currently, no imaging technique allows a reproducible quantitative exploration of the arterial trees of the hand, and therefore a satisfactory monitoring of transplants. Since 2014, flow MRI has been applied to the analysis …

Phase N/A

Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients

PRIMARY OBJECTIVES: I. To assess human papillomavirus (HPV) vaccine-type-specific seroconversion rates at 12-months post-transplantation among kidney transplant recipients who receive >= 1 doses of the recombinant human papillomavirus nonavalent vaccine (Gardasil 9 HPV vaccine) >= 30 days prior to transplantation. SECONDARY OBJECTIVES: I. To evaluate the following in adult kidney …


Approach to Vascular Access After Renal Transplantation

Patients after kidney transplantation during a routine visit will be asked to participate to the study. In eligible a number of studies will be conducted: detailed clinical examination routine laboratory tests lung ultrasound muscle strength with a dynamometer ultrasound assessment of upper limb vessels with assessment of fistula function (in …

Phase N/A

Belatacept in De Novo Heart Transplantation

Long-term outcomes after heart transplant remain suboptimal with renal failure and cardiac allograft vasculopathy contributing to morbidity and mortality. Belatacept is Food and Drug Administration (FDA) approved for use in kidney transplant recipients on the basis of two randomized controlled trials, which demonstrated important renal sparing benefits, a reduction in …


Influence of Genetic Polymorphism of Donor on Tacrolimus Concentration in Liver Transplant

This study will start with a retrospective data analysis. The investigators will use the electronic databases of National Taiwan University Hospital to identify patients who underwent liver transplantation, received tacrolimus and were still followed up at the outpatient clinic. Inclusion and exclusion criteria will be applied to screen appropriate participants, …

Phase N/A

Study to Evaluate Performance of LifePort Liver Transporter System a Machine Perfusion System for Liver Transplant

Prospective, randomized, multi-center study to show safe and effective use of whole liver preservation via hypothermic machine perfusion (HMP) as compared to livers preserved by static cold storage.

Phase N/A

Cyclosporine A Pretreatment and Kidney Graft Function

Organ donors included in the study are randomized to a control group receiving a placebo or an intervention group receiving 2.5 mg/kg of cyclosporine A before organ procurement. In the operating theater organs are harvested. Thereafter, harvested kidneys from these patients are transplanted to chronic kidney insufficiency patients. The management …