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Chronic Bronchitis Clinical Trials

A listing of Chronic Bronchitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (275) clinical trials

Increase Level of Physical Activity and Decrease Use of Health Care for People With COPD

COPD is a chronic and disabling disease with substantial morbidity and mortality. The disease is one of the top 5 leading causes of death worldwide and the high prevalence places a considerable burden on the health care system. The symptom burden of the disease; dyspnea, fatigue, impaired functional performance, decreased ...

Phase N/A

COPD Access to Pulmonary Rehabilitation Intervention

Conventional pulmonary rehabilitation (PR) programs are highly effective and the standard of care in patients with chronic obstructive pulmonary disease (COPD). PR faces two significant problems: (1) most patients with COPD who would benefit from PR cannot access it, and 2) there is no effective long-term strategy to maintain physical ...

Phase N/A

Tezepelumab COPD Exacerbation Study

This is a Phase 2a, multicenter, randomized, double-blind, placebo-controlled, parallel group study to evaluate the safety and efficacy of tezepelumab in adults with moderate to very severe chronic obstructive pulmonary disease (COPD) receiving triple inhaled maintenance therapy, and having had 2 or more documented COPD exacerbations in the 12 months ...

Phase

Anti-viral Effects of Azithromycin in Patients With Asthma and COPD

Asthma and COPD are responsible for considerable global morbidity and healthcare costs, primarily driven by exacerbations, i.e. acute flare-ups. Hence there is a clear need for better interventions preventing exacerbations. A majority of exacerbations are driven by infections, and in particular viral infections. Importantly, the anti-viral defense in asthma and ...

Phase

Automation of Oxygen Delivery in Spontaneous Ventilation (FreeO2) in Infants

This is a multi-center, randomized, open-controlled, multicentre trial. Patients will be included after a compendium of informed and express consent from both parents. They will then be randomized either in the "FreeO2" arm or in the "manual" arm for Oxygen therapy with manual flow adjustment. The SpO2 will be recorded ...

Phase N/A

Legend: TRELEGY Real World Chronic Obstructive Pulmonary Disease (COPD) Effectiveness Study

The primary purpose of this study is to assess the effectiveness of TRELEGY ELLIPTA single inhaler triple therapy (SITT) (fluticasone furoate/umeclidinium bromide/vilanterol [FF/UMEC/VI]) relative to non-ELLIPTA multiple inhaler triple therapies (MITT) of inhaled corticosteroids/long-acting beta2-adrenergic receptor agonists/muscarinic receptor antagonists (ICS/LABA/LAMA) within a routine clinical practice setting. This is a non-randomized, ...

Phase

A Study to Evaluate the Efficacy and Safety of Pirfenidone With Novel Coronavirus Infection

This study is a multi-center, randomized, open, blank-controlled, multi-stage clinical study. As there are no effective treatments, the project team will evaluate possible treatments (including but not limited to Pirfenidone) based on actual conditions. Ketone, Pirfenidone, lopinavir / ritonavir, remdesivir, single / polyclonal antibodies against coronavirus), explore the most effective ...

Phase

Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality

The population is expanding and aging. With the increasing aging population demographics and life expectancies, the number of very elderly patients (age 75) undergoing surgery is rising. Elderly patients constitute an increasingly large proportion of the high-risk surgical group. In 2010, patients aged 75 yrs and over represented only 2.1% ...

Phase N/A

Pivotal Study to Assess the Efficacy Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation

Approximately 68 weeks including a 4-week screening period, a 52-week treatment period, and 12 weeks of follow-up.

Phase

A Study on Whether Patients Prefer the Spiriva Respimat or the Spiriva Handihaler for Treating Their Chronic Obstructive Pulmonary Disease (COPD)

The objective of this study is to investigate the patient acceptability/preference of Respimat compared with Handihaler in patients with moderate to severe chronic obstructive pulmonary disease (COPD) to demonstrate the superiority of Respimat.

Phase