Graft-Versus-Host Disease (GVHD) Clinical Trials

A listing of Graft-Versus-Host Disease (GVHD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 241 clinical trials
SHR0302 and Steroid as First Line Therapy for Chronic GVHD

The purpose of this study is to evaluate the efficacy of SHR0302 in combination with Prednisone as first line therapy in patients with moderate to severe chronic graft-versus-host disease (GVHD

prednisone
immunosuppressive agents
shr0302
hematologic malignancy
acute graft-versus-host disease
  • 0 views
  • 26 Jan, 2021
  • 2 locations
Tildrakizumab for Prevention of Acute Graft-Versus-Host Disease

This is a phase 2 open-label trial designed to evaluate the efficacy of tildrakizumab in improving graft-versus-host disease (GVHD)-free relapse-free survival after myeloablative allogeneic

ejection fraction
bilateral oophorectomy
hematologic malignancy
lymphoid leukemia
hla-a
  • 0 views
  • 15 Sep, 2021
  • 1 location
Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

minimize graft versus host disease (GVHD) in leukemic and myelodysplastic patients who have had a partially mismatched bone marrow transplant (haploidentical).

ejection fraction
cyclophosphamide
chronic myeloid leukemia
lymphoid leukemia
remission
  • 2 views
  • 30 Mar, 2021
  • 1 location
FMT for Steroid Resistant Gut Acute GVHD

The study aims to evaluate the safety and efficacy of fecal microbiota transplantation (FMT) for the treatment of steroid resistant graft-versus-host-disease (GVHD) of the gut. This strategy

abdominal pain
graft versus host disease
diarrhea
acute graft-versus-host disease
  • 1 views
  • 24 Jan, 2021
  • 1 location
Clinical Studies of New Model Haploidentical Hematopoietic Stem Cell Transplantation

Building a new haploid transplanted model with high-dose CTXCD19-CART,donor CD34+ hematopoietic stem cell and Tregs,to prevent graft-versus-host disease(GVHD),reduce the infection,promote the

  • 3 views
  • 24 Jan, 2021
  • 1 location
Vorinostat for Graft vs Host Disease Prevention in Children Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

addition of Vorinostat to the standard preventive therapy (tacrolimus [or cyclosporine] / methotrexate) will reduce the incidence of graft versus host disease (GVHD) following allogeneic, myeloablative

cyclosporine
cns metastases
lymphoid leukemia
hodgkin's disease
tyrosine
  • 24 views
  • 09 Sep, 2021
  • 1 location
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

patients unable to receive further radiation). followed by a post-transplant graft-versus-host disease (GVHD) prophylaxis regimen of post-transplant cyclophosphamide (PTCy), tacrolimus (Tac), and

multiple myeloma
lymphoid leukemia
renal dysfunction
remission
residual tumor
  • 58 views
  • 01 Jun, 2021
  • 1 location
T Cell Receptor / TCD HCT in Patients With Fanconi Anemia

routine graft-versus-host disease (GVHD) immune suppression leading to earlier immune recovery and potentially a reduction in the risk of severe infections after transplantation.

ejection fraction
cyclophosphamide
colony stimulating factor
methylprednisolone
growth factor
  • 18 views
  • 02 Jun, 2021
  • 1 location
Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF)

, decreases spleen size and might diminish graft-versus-host disease (GvHD), thereby improving the outcome of SCT.

stem cell transplantation
graft versus host disease
pacritinib
  • 24 views
  • 03 Sep, 2021
  • 21 locations
Ikervis for DED Due to GVHD Post Allo-HSCT

Dry eye disease (DED) is a common sequelae of graft versus host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Since Ikervis is reported to be a safe and

  • 0 views
  • 26 Jan, 2021
  • 1 location