Diabetes Mellitus Types I and II Clinical Trials

A listing of Diabetes Mellitus Types I and II medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 56 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

cardiovascular disease
body mass index
hemoglobin a1c
  • 593 views
  • 24 Jun, 2021
  • 881 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

insulin
c-peptide
type 2 diabetes mellitus
metformin
fasting
  • 271 views
  • 23 Jun, 2021
  • 106 locations
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

metformin
insulin
type 2 diabetes mellitus
hemoglobin a1c
  • 0 views
  • 23 Jun, 2021
  • 161 locations
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CFZ533 on preservation of residual pancreatic -cell function in new onset T1DM in pediatric and young adult subjects.

immune tolerance
glutamic acid
tolerance test
c-peptide
diabetes
  • 10 views
  • 23 Jun, 2021
  • 11 locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

glucagon
glucagon-like peptide-1
hemoglobin a1c
diabetes
  • 0 views
  • 23 Jun, 2021
  • 90 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

cardiovascular disease
diabetes
heart disease
atherosclerosis
hypertension
  • 105 views
  • 22 Jun, 2021
  • 1 location
A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes

The purpose of this study is to evaluate the efficacy and safety of 2 doses of dulaglutide in Japanese participants with type 2 diabetes. The study duration is approximately 58 weeks.

sulfonylurea
body mass index
alpha-glucosidase inhibitor
hemoglobin a1c
  • 0 views
  • 16 Jun, 2021
  • 40 locations
Visualizing Beta Cells in Patients With a History of Gestational Diabetes

In order to evaluate the difference in beta cell mass in women with and without a history of gestational diabetes mellitus (GDM), investigators aim to compare quantitative PET imaging of the pancreas between these groups. Investigators propose to measure uptake of 68Ga-NODAGA-exendin-4 in the pancreatic beta cells of these women …

insulin
exenatide
tolerance test
type 2 diabetes mellitus
glucose tolerance test
  • 1 views
  • 24 Jun, 2021
  • 1 location
Identifying Therapeutic Targets of Accelerated Sarcopenia

The proposed research is designed to identify the mechanisms that can accelerate loss of muscle size, strength and physical function in type 2 diabetes and with hospitalization in older persons. About of older Americans have type 2 diabetes, and about of the hospitalizations in the USA involve persons older than …

sarcopenia
diabetes mellitus
type 2 diabetes mellitus
mini-mental state examination
diabetes
  • 152 views
  • 23 Jun, 2021
  • 1 location
Safety and Feasibility of a Low Carbohydrate Diet in Children With Type 1 Diabetes

Good glycemic control in individuals with Type 1 diabetes (T1D), has been proven to reduce the risk of diabetes-related complications. Despite technological advances such as the use of insulin delivery devices and continuous glucose monitoring, the average glycemic control in T1D is poor. Though dietary management plays a major role …

insulin
glycosylated hemoglobin
diabetic complication
diabetes
continuous glucose monitoring
  • 0 views
  • 23 Jun, 2021
  • 1 location