Squamous Cell Carcinoma Clinical Trials

People with Squamous Cell Carcinoma of the Head and Neck (SCCHN) are asked to participate in a research study being conducted by Montefiore Medical Center, investigating adoptive cell therapy (ACT) of autologous tumor infiltrating lymphocytes (TIL). Study Drug: LN-145 is cellular study drug that utilizes an autologous TIL manufacturing therapy, ...

This trial is an open-label, single arm phase II study assessing the tolerability and anti-tumour activity of afatinib when given in combination with a fixed dose of pembrolizumab in patients with squamous NSCLC, who progressed during or after first line platinum-based standard therapy and had no prior treatment with an ...

People with Head and Neck Squamous Cell Carcinoma (HNSCC) are asked to participate in a research study being conducted by Montefiore Medical Center.

To assess the efficacy of MEDI4736 monotherapy in terms of ORR.

All enrolled patients will receive CDX-3379 and cetuximab. All patients in the study will be closely monitored to determine if there is a response to the treatment and for any side effects that may occur.

People with advanced squamous cell carcinoma are asked to participate in a research study being conducted by Northwell Health.

This is an open-label, multicenter trial to collect long-term safety and efficacy data and to provide ongoing access to tisotumab vedotin for patients with solid tumors who have completed a tisotumab vedotin base trial.

Patients with advanced HNSCC after platinum-based palliative chemotherapy have a poor prognosis, with no well-defined standard treatment and a survival between 6 to 9 months. MVX-ONCO-1 is a patient specific, cell-based, active immunotherapy, where the patient's immune response to tumor cells is stimulated and/or increased by triggering an immune response ...

This study evaluates the use of ABI-1968, a topical cream, in the treatment of anal precancerous lesions in adults with and without human immunodeficiency virus (HIV) infection.

The purpose of this study is to learn more about the outcomes of treatment of throat and voice box cancers using transoral robotic surgery (TORS). TORS is a relatively new option involving the use of the da Vinci surgical robot to remove these cancers through the mouth.