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Adenocarcinoma Clinical Trials

A listing of Adenocarcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (768) clinical trials

A clinical trial sponsored by Gary Morrow for a research study of Prochlorperazine, Olanzapine, Dexamethasone, Netupitant/Palonosetron Hydrochloride

PRIMARY OBJECTIVES: I. To determine if control of nausea at cycle 2 in participants who experienced chemotherapy-induced nausea and vomiting (CINV) at cycle 1 is improved by the addition of either prochlorperazine or olanzapine to the control arm of netupitant, palonosetron and dexamethasone. SECONDARY OBJECTIVES: I. To determine if olanzapine ...


Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer

The trial is a Phase I/II trial evaluating the effect of LOAd703 in patients with pancreatic cancer, biliary cancer, ovarian cancer and colorectal cancer. LOAd703 is an oncolytic adenovirus serotype 5/35 encoding immunostimulatory transgenes: TMZ-CD40L and 41BBL. In Phase I, three doses (total viral load - 1x10e11, 5x10e11, 1x10e12 viral ...


Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer

Methods: This is a randomized trial to evaluate induction treatment with XELOX and Capecitabine-based chemoradiotherapy with or without aspirin in a high-risk population selected by MRI. High-risk will be defined by presence of at least one of the following criteria on high-resolution thin-slice MRI (3 mm): tumors extending to within ...


A clinical research study of Antiandrogen Therapy, Docetaxel for the treatment of Stage IV Prostate Adenocarcinoma AJCC v7

PRIMARY OBJECTIVES: I. To assess the clinical benefit of combining radical surgery ? cytoreductive radical prostatectomy (CRP) - with the best systemic therapy (BST) in men with newly diagnosed clinical M1a or M1b metastatic prostate cancer (mPCa). SECONDARY OBJECTIVES: I. To determine the impact of CRP+BST on time to biochemical ...


A clinical research study of ESK981 for the treatment of Castration-Resistant Prostate Carcinoma, PSA Progression, Metastatic Prostate Carcinoma, Castration Levels of Testosterone, Stage IV Prostate Adenocarcinoma AJCC v7

PRIMARY OBJECTIVES: I. To determine the PSA >= 50% response rate (PSA50) from baseline using the Prostate Cancer Working Group 3 (PCWG3) criteria to pan-VEGFR/TIE2 tyrosine kinase inhibitor CEP-11981 (ESK981) as a single agent in men with castration-resistant prostate cancer (CRPC) who have progressed on enzalutamide (an oral androgen-receptor inhibitor) ...


A clinical trial sponsored by Bristol-Myers Squibb for a research study for the treatment of Malignant neoplasm of kidney, Renal Cell Carcinoma

This is a French, nationwide, prospective, observational, multicenter study in participants diagnosed with renal call carcinoma, who start a new systemic therapy with nivolumab for the first time and within the market authorization approval, following a first or second-line therapy.

Phase N/A

A clinical research study of Cabozantinib, Avelumab

This is an open-label, non-controlled, non-randomized, phase I dose-finding, of Cabometyx + Avelumab, to establish safety, feasibility, and the maximum tolerated dose (MTD) or Recommended Phase 2 Dose (RP2D) of Cabometyx in combination with Avelumab, and to investigate preliminary efficacy. The MTD or RP2D determined in this study will be ...