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Adenocarcinoma Clinical Trials

A listing of Adenocarcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (285) clinical trials

The Analysis of WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) Increased Yield of Barrett's Esophagus and Esophageal Dysplasia

Patients will be recruited from participating institutions prior to planned routine care EGD with WATS3D brush samples and forceps biopsies. Eligibility will be reviewed and patients who are potentially eligible for the study will be approached regarding the study. If interested, participants will be consented and proceed with routine care ...

Phase N/A

Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types

The study plans to enrol up to 250 patients in total with between 20 and 50 patients assigned to each cohort according to indication, as follows: - Cohort 1: Non-clear cell RCC - Cohort 2: Rare head and neck cancer - Cohort 3: Rare skin cancer - Cohort 4: MSI-nonCRC ...


MGCD516 Combined With Nivolumab in Renal Cell Cancer (RCC)

Study Groups: If you are found to be eligible to take part in this study, you will be assigned to 1 of 4 dose levels based on when you join this study. The dose of MGCD516 you receive will depend on how well previously enrolled patients tolerated the study drug. ...


Efficacy and Safety Study of Pembrolizumab (MK-3475) Versus Paclitaxel in Asian Participants With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Who Progressed After First-line Therapy With Platinum and Fluoropyrimidine (MK-3475-063/KEYNOTE-063)

The study will compare the efficacy and safety of treatment with pembrolizumab (MK-3475) versus paclitaxel in Asian, programmed death-ligand 1 (PD-L1) positive participants with advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma who have progressed after failure of any combination chemotherapy containing a platinum and a fluoropyrimidine agent. The primary study ...


A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy

This is a Phase III, multicenter, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of atezolizumab versus placebo in participants with RCC who are at high risk of disease recurrence following nephrectomy.


An Investigational Immuno-Therapy Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Renal Cell Carcinoma

The purpose of this study is to evaluate safety and efficacy of different administration regimens of nivolumab plus ipilimumab in subjects with renal cell carcinoma.


Sunitinib Followed by Avelumab or the Reverse for Metastatic Renal Cell Carcinoma

OUTLINE: This is a multi-center trial. Eligible subjects will be randomized and stratified to one of two arms: FIRST-LINE INVESTIGATIONAL TREATMENT ARM A: - Avelumab 10mg/kg intravenously (IV) on Day 1 (D1) and Day 15 (D15) of every 28 day cycle until documented disease progression per Immune-related Response Evaluation Criteria ...


Docetaxel Plus Nivolumab or Docetaxel Alone in Patients With Advanced NSCLC Previously Treated With a PD-1 or PD-L1 Inhibitor

OUTLINE: This is a multi-center study. INVESTIGATIONAL TREATMENT: Eligible subjects will be randomized in 1:1 ratio to receive treatment with either: Arm A: docetaxel 75 mg/meters squared (mg/m^2) plus nivolumab 360 mg IV every 21 days Arm B: docetaxel alone 75 mg/m^2 every 21 days For both treatment arms, 21 ...


Efficacy and Safety Trial of Apatinib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Patients With Gastric Cancer

The purpose of this study is to evaluate the clinical benefit and safety of Apatinib plus Best Supportive Care in comparison to Placebo plus Best Supportive Care in patients with advanced or metastatic gastric cancer


Tucatinib (ONT-380) and Trastuzumab for Patients With HER2-positive Metastatic Colorectal Cancer (MOUNTAINEER)

This is a phase II trial that will study how well tucatinib (ONT-380) and trastuzumab work in treating patients with colorectal cancer with a specific genetic marker (human epidermal growth factor receptor 2 - HER2) that has spread to other places in the body or has come back and cannot ...