Antiphospholipid Syndrome Clinical Trials

A listing of Antiphospholipid Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 20 clinical trials
Multi-center Randomized Pilot Clinical Trial on Remote Ischemic Conditioning in Acute Ischemic Stroke Within 9 Hours of Onset in Patients Ineligible to Recanalization Therapies (TRICS-9)

Phase II, prospective, randomized, multicenter, open-label, pilot clinical trial comparing remote ischemic conditioning (RIC) plus standard medical therapy to standard medical therapy alone, in patients with acute ischemic stroke within 9 hours of stroke onset that are not eligible to recanalization therapies.

  • 10 views
  • 19 Oct, 2022
  • 3 locations
The BeLimumab Antiphospholipid Syndrome Trial (BLAST) (BLAST)

AIM: The primary objective of the BeLimumab Antiphospholipid Syndrome Trial (BLAST) is to evaluate the safety and tolerability of belimumab for up to 24 months in patients with persistent aPL

anticoagulant
thrombosis
lupus
warfarin
immunoglobulin g
  • 40 views
  • 05 Jun, 2022
  • 1 location
Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia

To evaluate the safety and efficacy of zanubrutinib in the treatment of antiphospholipid syndrome with secondary thrombocytopenia in 10 patients.

cyclosporine
rituximab
cyclophosphamide
  • 0 views
  • 09 Jun, 2022
  • 2 locations
Telitacicept in Primary APS Patients

This is a single-arm pilot study in Peking Union Medical College Hospital. Telitacicept will be added on traditional antithrombotic and immunosuppressive treatment in primary antiphospholipid

anticoagulant
thrombosis
stroke
glycoprotein
lupus
  • 3 views
  • 22 Oct, 2021
  • 1 location
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this regimen will improve pregnancy outcomes. All enrolled patients will receive certolizumab, and

anticoagulant
heparin
certolizumab pegol
aspirin
tumor necrosis factor-alpha
  • 243 views
  • 14 May, 2022
  • 2 locations
Effect of Injectable Anticoagulants on Research for a Circulating Lupus-type Anticoagulant (ANTICOLA)

The aim is to assess the effect of injectable anticoagulants (unfractionated heparin (UFH), low molecular weight heparins (LMWH), fondaparinux, danaparoid, argatroban) on lupus anticoagulant testing assays over broad anti-Xa activity ranges and to establish their potential for causing false-positive or false-negative results.

anticoagulant
thrombosis
lupus
heparin
Accepts healthy volunteers
  • 0 views
  • 29 Jun, 2022
  • 1 location
Hydroxychloroquine for Prevention of Recurrent Miscarriage.

Antiphospholipid Syndrome. Hydroxychloroquine (HQ) is a molecule whose properties (anti-thrombotic, vascular-protective, immunomodulatory, improved glucose tolerance, lipid-lowering, anti-infectious) could

antiphospholipid antibodies
thrombophilia
aspirin
antiphospholipid syndrome
hydroxychloroquine
  • 420 views
  • 26 Nov, 2021
  • 26 locations
HYDROxychloroquine in Syndrome Primary AntiPhospholipid (HYDROSAPL)

Antiphospholipid syndrome (APS) is defined by thrombosis or obstetric complication (≥ 3 spontaneous miscarriages or fetal death or prematurity <34 weeks gestation-related amenorrhea (SA

  • 7 views
  • 12 Mar, 2022
  • 1 location
Efficacy and Safety of Eltrombopag + CSA in Patients With Moderate Aplastic Anemia (EMAA)

The aim of this study is to improve treatment of Moderate Aplastic Anemia (MAA) by evaluating the safety and efficiency of Eltrombopag as a new treatment option in patients with therapy requiring MAA.

platelet count
blood transfusion
neutrophil count
hypocellular bone marrow
aplastic anemia
  • 78 views
  • 22 Jan, 2021
  • 1 location
Placental Pathology and Inflammatory Factor Analysis of OAPS

This investigation is on placental pathological changes and inflammatory factors associated with obstetric antiphospholipid syndrome.

Accepts healthy volunteers
  • 0 views
  • 24 May, 2022
  • 1 location