Mood Disorders (Pediatric) Clinical Trials

A listing of Mood Disorders (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 54 clinical trials
Intervention to Prevent Peer Violence & Depressive Symptoms Among At-Risk Adolescents (iDOVE2)

The purpose of this investigation is to test the efficacy of "iDOVE2" (a brief emergency department introductory session and longitudinal automated text-message depression prevention program for high-risk teens), and to determine the most potent and parsimonious combination of intervention components for preventing peer violence and depressive symptoms among at-risk youth.

depressed mood
physical violence
depression
behavioral therapy
violence
  • 22 views
  • 12 Feb, 2022
  • 1 location
Message-Based Psychotherapy and Digital Treatment Sequences for Depression

This partnership between Talkspace and the UW ALACRITY Center will determine how effective unlimited text-based psychotherapy for depression is when compared to once-a-week psychotherapy. This study will also determine what the best treatment options are for people who are not responding well to either unlimited texting or weekly psychotherapy. The …

depression
anxiety
depressed mood
  • 22 views
  • 22 Apr, 2022
  • 1 location
Follow-up Study With Clinical Vitamin D Supplementation Trial on Patients With Depression (DepFuD)

Depression affects 350 million people worldwide. In the light of the global disease burden statistics, the efficacy of current treatments for depression appears insufficient. Thus, research on novel treatment interventions and predictors for good treatment response are warranted. Earlier prospective follow-up studies and intervention studies suggest that several bio-psychosocial factors, …

psychiatric disorder
severe depression
recurrent depression
depressed mood
antidepressants
  • 4 views
  • 23 Jan, 2021
  • 1 location
Collaborative and Stepped Care in Mental Health (COMET) (COMET)

The aims of COMET are the implementation and evaluation of effectiveness and cost-effectiveness as well as processes of a collaborative and stepped care model for depressive, anxiety, somatoform and/or alcohol abuse disorders within a multiprofessional network in comparison to routine care. In a cluster-randomized controlled effectiveness trial 570 patients will …

anxiety
social phobia
agoraphobia
drug abuse
remission
  • 30 views
  • 15 Feb, 2022
  • 1 location
Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and Adults

Objective: This protocol uses functional magnetic resonance imaging (fMRI) to examine neuro-cognitive correlates of pediatric and adult mood and anxiety disorders. The primary goal of the project is to document, in pediatric anxiety disorders and major depression, perturbations in brain systems mediating attention biases, fear conditioning, emotional memory, and response …

anxiety
mood disorder
psychiatric disorder
social interaction
behavioral therapy
  • 736 views
  • 21 Oct, 2022
  • 1 location
Suicide Prevention Among Recipients of Care

Randomized controlled trial to determine the best brief suicide prevention intervention for adults and adolescents who screen positive for suicidal ideation or behavior in emergency departments or primary care clinics. Aim 1: Compare the effectiveness of two brief suicide prevention interventions (safety planning intervention plus structured phone-based follow-up from a …

suicide
suicidal
suicide prevention
  • 0 views
  • 03 Oct, 2021
  • 1 location
Anti-inflmmation Treatment in Mood Disorder and Deep Learning Prediction Model

This three-year study will enroll 180 patients with mood disorders (90 patients with major depressive disorder and 90 patients with bipolar disorder) and high pro-inflammatory cytokine levels. They will be randomly assigned to three groups of aspirin, statin and control groups for 12 weeks according to the disease group. The …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Background Electroconvulsive therapy (ECT) is used to treat people with severe depression. During ECT, the brain is given electric pulses that cause a seizure. Although it is effective, it can cause side effects, including memory loss. Researchers want to study a new way to give ECT called iLAST. Objective To …

anesthesia
electroconvulsive therapy
severe depression
depressed mood
scid
  • 6 views
  • 23 Oct, 2022
  • 1 location
An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empirically-derived algorithm that specifies whether, when, and how to augment IPT-A. Two …

sertraline
psychotherapy
selective serotonin reuptake inhibitors
depression
depressed mood
  • 109 views
  • 06 May, 2022
  • 1 location
Cerebral Neuroinflammation During Major Depressive Episode

the investigators make the following assumptions: 1) neuroinflammation in MDD can be measured by the [18 F ] DPA- 714 ; 2) it is accompanied by anatomical and functional changes in the frontal subcortical loops, strongly involved in MDD ; 3) neuroinflammation in patients might be a biomarker related to …

blood tests
antidepressants
remission
major depressive disorder
Accepts healthy volunteers
  • 7 views
  • 06 Nov, 2021
  • 4 locations