Cystic Fibrosis Clinical Trials

A listing of Cystic Fibrosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate

pulmonary function test
mucolytics
cystic fibrosis
cough
macrolides
  • 6 views
  • 22 Apr, 2022
  • 14 locations
CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

CHED- Congenital Endothelial Endothelial Dystrophy is a condition that causes corneal cloudiness. Since, currently only surgery is being done to cure this condition, we are taking up the research of using topical eye drops for this condition which is a very simple and easy method. Also, there are no significant …

  • 9 views
  • 27 Apr, 2021
  • 1 location
Planning Treatment for Oesophago-gastric Cancer: a Maintenance Therapy Trial (PLATFORM)

To evaluate the efficacy of maintenance therapies following completion of standard first-line chemotherapy in patients with locally advanced or metastatic HER-2 positive or HER-2 negative oesophago-gastric adenocarcinomas.

liver metastasis
cancer
gastric cancer
ramucirumab
blood transfusion
  • 0 views
  • 26 Jan, 2022
  • 1 location
Rituximab in Patients With ST-elevation Myocardial Infarction (RITA-MI2)

The main objective is to compare the effect of a single injection of two doses of rituximab versus placebo on 6 months left ventricular systolic function, using CMR, in patients who have had an acute anterior STEMI. The primary endpoint is the left ventricular ejection fraction (LVEF) by CMR at …

ischemia
stemi
angiography
  • 0 views
  • 17 Jun, 2022
  • 1 location
Trikafta in Cystic Fibrosis Patients

most suitable for cystic fibrosis modulator therapy.

pulmonary disease
ivacaftor
pancreatic enzyme
bronchiectasis
nasal potential difference
  • 8 views
  • 27 Apr, 2022
  • 3 locations
Safety Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis

This is a single center, open label, Phase IIa, multiple-ascending dose study in which subjects with mild to moderate Cystic Fibrosis and non CF bronchiectasis (n12) will be enrolled.

antibiotics
fibrosis
bronchiectasis
cystic fibrosis
  • 0 views
  • 25 Jun, 2021
  • 3 locations
Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis

The main objective of this clinical pilot study is to evaluate the feasibility and impact of a home-based exercise program on clinical and patient-centered outcomes in adult with cystic fibrosis

pulmonary rehabilitation
fibrosis
cystic fibrosis transmembrane conductance regulator
  • 0 views
  • 23 Mar, 2022
  • 1 location
Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

The purpose of this study is to assess the efficacy of metformin to improve airway ion channel function in those with CF-related diabetes (CFRD)

diabetes
elexacaftor
ivacaftor
tezacaftor
insulin
  • 0 views
  • 12 Mar, 2022
  • 1 location
Phase II Study of a Nebulised Nitric Oxide Generating Solution in Patients With Cystic Fibrosis (NOMAB)

To evaluate the change in M. abscessus cfu/g in induced sputum samples from baseline to the end of treatment with RESP301 in patients with cystic fibrosis who have treatment-naïve or

nitric oxide
fibrosis
pulmonary disease
  • 0 views
  • 07 Jul, 2022
  • 1 location
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis

safety of brensocatib compared to placebo in participants with cystic fibrosis (CF) over the 4-week treatment period.

fibrosis
body mass index
  • 0 views
  • 29 Jul, 2022
  • 19 locations