Cystic Fibrosis Clinical Trials

A listing of Cystic Fibrosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 257 clinical trials
Featured trial
A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

A research study for patients with cystic fibrosis who might have a condition called Fibrosing Colonopathy (FC).

  • 07 Nov, 2020
  • 1 location
Featured trial
Pancreatic Insufficiency

diseases, including cystic fibrosis (CF), chronic pancreatitis (CP), and pancreatic cancer. This study will assess clinical symptoms when participants with CF or CP are treated with Creon with alternate

chronic pancreatitis
pancreatic insufficiency
disease or disorder
pancreatic enzyme
  • 27 Jun, 2022
  • 1 location
Featured trial
Role of Genetic Factors in the Pathogenesis of Lung Disease

older with CF. Children will not be enrolled in the optional CT sub-study unless they have had a standard CT scan for medical purposes to use in comparison. One additional low dose radiation CT scan of

pulmonary disease
pulmonary fibrosis
  • 23 Nov, 2020
  • 1 location
Featured trial
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

Background: Severe aplastic anemia (SAA) and myelodysplastic syndrome (MDS) are bone marrow diseases. People with these diseases usually need a bone marrow transplant. Researchers are testing ways to make stem cell transplant safer and more effective. Objective: To test if treating people with SAA or MDS with a co-infusion of …

myelodysplastic syndrome (mds)
myelodysplastic syndromes
anemia studies
aplastic anemia
  • 22 Dec, 2020
  • 1 location
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib Administered Once Daily for 52 Weeks in Subjects With Non-Cystic Fibrosis Bronchiectasis - The ASPEN Study (ASPEN)

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

  • 20 Sep, 2022
  • 330 locations
A Randomized, Subject- and Investigator-blinded, Placebo-controlled, Parallel Group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of QBW251 in Patients With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate

cystic fibrosis
pulmonary function test
  • 18 Sep, 2022
  • 16 locations
Prednisone in Cystic Fibrosis Pulmonary Exacerbations (PIPE)

This will be a 5 year randomized, double blind, placebo controlled trial of 7 days of oral prednisone in cystic fibrosis (CF) patients receiving intravenous (IV) antibiotic treatment for a

  • 03 Mar, 2022
  • 12 locations
Home Airway Clearance in CF Patients

Regular bronchial clearance is essential in patients with cystic fibrosis for their bronchial health. SIMEOX (Physio-Assist, Aix en Provence, France) is an innovative medical device for the

  • 25 Aug, 2021
  • 6 locations
4D-710 in Adult Patients With Cystic Fibrosis (CF)

This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with CF who are ineligible for or unable to tolerate CFTR modulator therapy.

cftr gene
forced expiratory volume
cystic fibrosis transmembrane conductance regulator
  • 25 Jul, 2022
  • 6 locations
Trial on The Efficacy of Hypertonic Saline on Non-CF CSLD.

To determine the efficacy of nebulized 5% hypertonic saline on cough severity and quality of life, in children with non-CF CSLD. Secondary Aims: To determine the:

  • 24 May, 2022
  • 1 location