Arthritis and Arthritic Pain (Pediatric) Clinical Trials

A listing of Arthritis and Arthritic Pain (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 104 clinical trials
Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial (SPEED)

SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm …

adalimumab
leflunomide
anti-rheumatic drugs
sulfasalazine
methotrexate
  • 2 views
  • 02 Jun, 2022
  • 1 location
Symptomatic Management of Lyme Arthritis

Lyme arthritis resolves with appropriate antimicrobial treatment in a majority of patients, but 10-20% of patients develop antibiotic-refractory Lyme arthritis with prolonged arthritis symptoms and treatment courses. Excessive up-regulation of the inflammatory process has been shown in patients with antibiotic-refractory Lyme arthritis. The over-expressed pro-inflammatory cell mediators are downstream of …

mediators
antibiotic therapy
NSAID
cytokines
naproxen
  • 104 views
  • 20 Nov, 2021
  • 1 location
Diet Interventions in Psoriatic Arthritis (DIPSA)

The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).

body mass index
arthritis
anti-rheumatic drugs
DMARD
  • 0 views
  • 23 Mar, 2022
  • 2 locations
The MEDIPSA Clinical Trial

The main purpose of this study is to validate the positive effect of "Omnibiotic Stress Repair" on patients with active psoriatic Arthritis.

  • 0 views
  • 28 Mar, 2021
  • 1 location
Efficacy of Secukinumab Compared to Ustekinumab in Adults With Active Psoriatic Arthritis and Failure of TNFα-Inhibitor Treatment (AgAIN)

The purpose of this study is to compare the safety and efficacy of secukinumab and ustekinumab in patients with active psoriatic arthritis who showed failure to previous TNFα-inhibitor treatment

plaque psoriasis
dactylitis
anti-rheumatic drugs
secukinumab
psoriasis
  • 1 views
  • 04 Oct, 2022
  • 28 locations
The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis (OPT-JIA)

Far too many kids and families live in dread over the weekly nausea and vomiting caused by methotrexate - a medicine that controls joint swelling in Juvenile Arthritis patients. If methotrexate is not tolerated, expensive alternative biological medications may be started. This registry-based pragmatic randomized controlled trial will evaluate if …

methotrexate
uveitis
arthritis
swelling
  • 42 views
  • 18 Feb, 2022
  • 2 locations
Tablet-based Cognitive Behavioral Intervention for Older Adults With Arthritis Fatigue

The purpose of this project is to pilot test a long-term effect of Tab-G (tablet-based cognitive behavioral group education intervention). The investigators will evaluate the effect of Tab-G, relative to usual care group, on (a) daily steps, (b) fatigue level, (c) self-efficacy and (d) quality of life. Tab-G participants will …

  • 0 views
  • 11 May, 2022
  • 1 location
Preventing Extension of Oligoarticular Juvenile Idiopathic Arthritis JIA (Limit-JIA) (Limit-JIA)

This is a research study to test whether a once-weekly injection of abatacept will prevent the progression of Juvenile Idiopathic Arthritis (JIA) to a more severe form.To evaluate the effectiveness of a 24-week course of treatment with abatacept plus usual care versus usual care to prevent polyarthritis (5 joints), uveitis, …

biologics
polyarthritis
uveitis
cancer
abatacept
  • 2 views
  • 04 Oct, 2022
  • 13 locations
Strategies Towards Personalised Treatment in Juvenile Idiopathic Arthritis (JIA): The MyJIA Trial. (MyJIA)

Inhibitors of tumour necrosis factor (TNFa) reduce inflammation in patients with juvenile idiopathic arthritis (JIA), but only 20-40 percent achieve a state of no or very little disease activity. Tailored glucocorticoid joint injections are widely used (usually in general anaesthesia), but no controlled studies have addressed the effect of this …

  • 0 views
  • 12 Oct, 2022
  • 5 locations
Understanding Cognition, Oxytocin & Pain in Elders (UCOPE)

Osteoarthritis (OA) represents a significant cause of disability worldwide and the knee is the most commonly affected joint. Oxytocin (OT) is a mediator of endogenous analgesia in animal and human studies. This proposal will test the efficacy and safety of self-administered intranasal OT over 4-weeks in older individuals relative to …

osteoarthritis of knee
analgesia
osteoarthritis
  • 0 views
  • 04 Oct, 2022
  • 2 locations