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Abdominal Surgery Clinical Trials

A listing of Abdominal Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (69) clinical trials

Functional Outcome After Incisional Hernia Repair: Open Versus Laparoscopic Repair

Midline incisional hernia is reported from 0,5 to 11% after abdominal operations. Discomfort, pain, body image alteration and diminished quality of life influences functional well being. Alteration in pulmonary function, risk of visceral incarceration or cutaneous complications are potential medical complications. Primary repair without mesh reinforcement is almost abandoned because ...


A Pilot Study of Bupivacaine Infusion in Abdominal Surgery

Pain in the post-operative period has been a limiting factor delaying recovery following abdominal surgery. Furthermore, it has been associated with several complications including ileus, urinary retention, delay to tolerating oral intake and enteral feeds, thrombo-embolic complications, and respiratory complications such as atelectasis and pneumonia. Diminishing pain in the post-operative ...


Fibrinogen as an Alternative to FFP in Aortic Surgery.

Thoracoabdominal aneurysm (TAAA) repair is a major elective vascular operation associated with a large blood loss and potentially life-threatening clotting abnormalities. Theses clotting abnormalities are principally treated using fresh frozen plasma (FFP) (derived from human blood donations), the administration of which carries a number of risks including virus transmission (human ...


Effect of PEP on Oxygen Saturation and Carbon Dioxide After Abdominal Surgery

Background Patients who have undergone thoracic and abdominal surgery receive lung atelectases after surgery. This in turn leads to poorer oxygenation, longer healing time and can contribute to increased risk of complications. In order to counteract atelectasis, patients are instructed by a physiotherapist to take deep inspiratory breaths and expire ...

Phase N/A

Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)

This will be a prospective study in patients aged between 18 and 70 years old who have already been screened and planned for elective bariatric surgery. In bariatric surgery, a large portion of the stomach will be removed. Pneumoperitoneum is also known as the abdominal pressure which will be the ...

Phase N/A

Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery

Postoperative pain continues to be inadequately managed and is the most common reason for the delay in discharge and unplanned hospital admission after surgery. Opioids remain the mainstay for postoperative analgesia. However, there is a continuous search for adjuvant therapies to reduce the doses of opioids and their related adverse ...


Individualized Goal-directed Sufentanil Administration Versus Standard Therapy in Patients Undergoing Major Abdominal Surgery

Postoperative respiratory complications are the second most frequent complications after surgery, and a major burden in health care. Postoperative hypoxemia, which is one of the most meaningful factors associated with poor patient outcomes, is common after general anesthesia with rates as high as 30-50% in patients after abdominal surgery, even ...

Phase N/A

Individualized Perioperative Hemodynamic Goal-directed Therapy in Major Abdominal Surgery (iPEGASUS-trial)

Postoperative mortality in patients undergoing surgery is on average still 4% in Europe as evaluated recently in a cohort study across 28 European countries and is considered to be even higher in high risk surgery. But besides this significant risk of death, in particular moderate and severe postoperative complications, affecting ...

Phase N/A

Prospective Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches

According to the peripheral trigger theory of migraine headaches, nociceptive inputs from irritated or compressed cranial nerve branches can lead to neurovascular changes in the brain that cause migraine headaches. Advanced treatments aimed at deactivating the peripheral trigger points can be administered to patients who have failed medical management of ...

Phase N/A

Prevena Incision Management System vs Conventional Management for Wound Healing

All patients submitted to contaminated or dirty abdominal surgery have more risk of surgical site infections. The investigators intend to randomize this kind of patients and comparison wound healing after dressed with incisional negative pressure wound therapy or standard dressing. In the study group INPWT (Prevena) is positioned immediately next ...