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Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (24) clinical trials

Deep Brain Stimulation Surgery for Movement Disorders

Objective The objective of this protocol is to provide DBS surgery and to collect physiology and efficacy data related to DBS therapy and motor and cognitive function in people with medically refractory Parkinson s disease (PD), dystonia, and essential tremor (ET). All treatment under this protocol will be based on …

Phase N/A

A Study to Evaluate the Effectiveness and Safety of ExAblate MRgFUS on Essential Tremor

The objective of this prospective, multi-site, single-arm study is to test the efficacy of treatment using the ExAblate Transcranial System and to further demonstrate safety in medication-refractory tremor in subjects with essential tremor (ET). Safety: To evaluate the incidence and severity of adverse events (AE/AEs) associated with ExAblate Transcranial MRgFUS …

Phase N/A

Deep Brain Stimulation Therapy in Movement Disorders

Objective The purposes of this protocol are: To train NINDS Medical Neurology Branch fellows and other trainees in all aspects of deep brain stimulation (DBS) treatment of medically refractory Parkinson s disease (PD), dystonia, essential tremor (ET) and other indications, including patient selection, physiology, and programming and management after DBS …

Phase N/A

A Study to Evaluate the Efficacy Safety and Tolerability of SAGE-324 in Participants With Essential Tremor

This is a phase 2, double-blind, placebo-controlled study to evaluate the safety and efficacy of SAGE-324 compared to placebo on upper limb tremor reduction in individuals with essential tremor (ET).


Algorithms for Programming DBS Systems for ET

Primary Endpoint/Event/Outcome: Endpoint: Identify the neural pathways within the brain that are involved in the reduction of action and postural tremor using directional DBS leads and advanced computational optimization algorithms. Event: Using anatomical segmentation of high-field 7-Tesla MRI and diffusion tensor imaging from 25 human ET subjects, the investigators will …

Phase N/A

Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor

The objective of this prospective, multi-site, single-arm, open-label study is to capture the safety and efficacy (outcome) of bilateral staged Exablate treatment in subjects with bilateral medication-refractory essential tremor (ET). The staged second procedure will be performed at least 9 months after the first side. The benefit of real-time feedback …

Phase N/A

Bilateral Treatment of Medication Refractory Essential Tremor

The purpose of this study is to see if the MR-guided focused ultrasound (MRgFUS) thalamotomy procedure can be performed on both sides of the brain safely and effectively to reduce bilateral tremor.

Phase N/A

Responsive Deep Brain Stimulator for Essential Tremor

The purpose of this study is to investigate brain signals related to intention tremor in essential tremor in order to deliver deep brain stimulation only when the patient is showing symptoms. By delivering stimulation only when needed, the investigators hypothesize that the treatment will be more effective, will cause fewer …

Phase N/A

Evaluation of the Infinity Deep Brain Stimulation Electrode Screening Mode Tool

This is a prospective, non-randomized, single-arm, multi-center, post-market clinical investigation designed to evaluate Abbott's Informity tool for Infinity DBS systems. This clinical investigation will be conducted at up to 5 centers in the United States. 40 patients will be enrolled in the study. Of these subjects, 20 will have PD …

Phase N/A

Trial of Cannabis for Essential Tremor

Essential tremor (ET) is the most common neurological movement disorder, affecting up to 1% of the population and up to 5% of individuals over the age of 65. ET is characterized by often disabling tremors that occur when an individual moves. The tremors most commonly affect the hands, head, voice, …