Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 22 clinical trials
Bilateral Essential Tremor Treatment With FUS (BEST-FUS)

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with who previously underwent successful and uncomplicated MRgFUS thalamotomy for essential

movement disorder
  • 26 May, 2022
  • 1 location
The Swedish Essential Tremor (SWEET) Trial (SWEET)

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

brain stimulation
movement disorder
  • 05 Jun, 2022
  • 5 locations
Optimization of VIM Targeting in Essential Tremor Surgery (Opti-VIM)

Deep brain stimulation (DBS) for essential tremor is based on the intermedius ventralis nucleus of the thalamus (VIM) stimulation. This structure is however very difficult to target, as it

  • 14 May, 2022
  • 2 locations
Study to Evaluate SAGE-324 in Participants With Essential Tremors

The primary purpose of this study is to evaluate the dose-response relationship of different doses of SAGE-324 on upper extremity tremor in participants with essential tremors (ET).

limb tremor
intention tremor
  • 27 May, 2022
  • 6 locations
Neurophysiologic Assessment of ET Patients Treated by Vim DBS

Essential tremor is a chronic and progressive neurological disease characterized by upper limb tremor. This is one of the most frequent movement disorders. Most of the time the disease worsens

  • 06 Jun, 2022
  • 1 location
A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor

This study will be a single-centre, prospective, single-arm, open-label, 12-week pilot trial assessing the safety and preliminary efficacy of a second MR-guided focused ultrasound (MRgFUS) thalamotomy on the naïve brain hemisphere after 48 weeks or more of the first MRgFUS thalamotomy in patients with medication-refractory ET. This study will be …

  • 29 May, 2022
  • 1 location
DBS of Posterior Subthalamic Area (PSA) and Ventral Intermediate Nucleus (VIM) in Essential Tremor (ET)

Deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus (VIM) is an FDA approved treatment for medication refractory essential tremor (ET). However, VIM stimulation can

  • 25 May, 2022
A Clinical Trial of 3 Doses of PRAX-944 in Participants With Essential Tremor

of adults with essential tremor. Blood levels of PRAX-944 will also be measured throughout the trial.

intention tremor
  • 15 Jun, 2022
  • 22 locations
A Clinical Trial of PRAX-114 in Participants With Essential Tremor

This is a 2-part clinical trial to evaluate the safety, tolerability, pharmacokinetics, and efficacy of PRAX-114 in participants with essential tremor (ET). Part A is a randomized, double-blind

  • 05 Jun, 2022
  • 3 locations
A Study To Assess the Safety and Efficacy of JZP385 in the Treatment of Adults With Moderate to Severe Essential Tremor (ET)

This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP385 in the treatment of adult participants with moderate to severe ET.

  • 13 Jun, 2022
  • 16 locations