Lung Injury Clinical Trials

A listing of Lung Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 228 clinical trials
Respiratory Mechanics in Brain Injured Patients

The hypothesis is that brain injury patients have alterations of the respiratory system related to intraabdominal pressure. Furthermore application of moderate levels of PEEP may improve respiratory function in these patients.

mechanical ventilation
positive end expiratory pressure
lung injury
  • 16 views
  • 07 Nov, 2020
  • 1 location
Mid and Standard Frequency Ventilation in Infants With Respiratory Distress Syndrome

ventilator-free days after randomization and reduce the risk of ventilator induced lung injury.

ventilator-induced lung injury
respiratory distress
lung injury
pulmonary surfactant
  • 43 views
  • 26 Jan, 2021
  • 2 locations
Noninvasive Positive Pressure Ventilation for ALI/ARDS:a Multicentre Randomized Controlled Trial

with appropriate inspired oxygen concentrations, NPPV would prevent intubation and hence avert the poor outcome associated with the need of invasive ventilation in patients with ALI/ARDS.

intubation
positive pressure ventilation
intermittent positive pressure ventilation
  • 26 views
  • 07 Nov, 2020
  • 1 location
Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure Fraction of inspired Oxygen 100 / peripheral Oxygen Saturation, OSI = MAPxFiO2x100/SpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.

FIO2
  • 0 views
  • 05 Jul, 2021
  • 1 location
The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study

-reperfusion lung injury in lung transplant patients. 2. Aims of the Study: The purpose of the trial is to study the effect of exogenous calf surfactant (calfactant) on the

graft failure
surfactant
  • 1 views
  • 07 Nov, 2020
  • 1 location
Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema

vascular dilatation to characterize emphysema susceptibility in a normal smoking population. The investigators will correlate DECT measures of perfusion with lung injury measured by single photon emission

dect
cotinine
forced expiratory volume
sildenafil
pulmonary function test
  • 66 views
  • 13 Feb, 2021
  • 1 location
Smoking Cessation and Functional CT Assessment

The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema.

cotinine
sildenafil 20 mg
forced expiratory volume
COPD
pulmonary disease
  • 141 views
  • 24 Feb, 2021
  • 1 location
Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)

The purpose of this study is to understand if it is safe and useful to perform SGB (Stellate Ganglion Block) in patients who have severe lung injury Acute Respiratory Distress Syndrome (ARDS

covid-19
acute respiratory distress
edema
respiratory distress
lung injury
  • 100 views
  • 26 Jan, 2021
  • 1 location
LIBERATE Trial in COVID-19

The study aims to evaluate the reduction in severity and progression of lung injury with three doses of lipid ibuprofen in patients with SARS-CoV-2 infections.

SARS
covid-19
FIO2
ventilator-induced lung injury
pao2
  • 23 views
  • 26 Jan, 2021
The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19)

This is a multicenter, single-treatment study. Subjects will consist of adults with COVID-19 associated acute lung injury who are being cared for in a critical care environment.

  • 0 views
  • 24 Sep, 2021
  • 7 locations