Lung Injury Clinical Trials

A listing of Lung Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 232 clinical trials
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Preservation of Blood in Extremely Preterm Infants

Current clinical protocols for blood sampling and analyses in extremely preterm infants rely on an infrastructure adapted to and developed for adult medicine. Excessive blood sampling volumes and the resulting loss of fetal blood components are related to neonatal morbidity. This randomised trial aims to provide evidence that preservation of …

  • 0 views
  • 25 May, 2021
  • 1 location
None
Follow-up Study of Safety and Efficacy in Subjects Who Completed PNEUMOSTEM Phase II (MP-CR-012) Clinical Trial

This is a follow-up study to investigate the long-term safety and efficacy of PNEUMOSTEM versus placebo, for the treatment of BPD in premature infants. Subjects who participated in and completed the initial stage of the Phase II trial (NCT03392467) will be followed-up until 60 months of corrected age

premature birth
prematurity
  • 0 views
  • 25 Jan, 2021
None
Examination of Pirfenidone (Esbriet ) Therapy in Coal Workers' Pneumoconiosis With Pulmonary Fibrosis

Examination of pirfenidone (Esbriet) therapy in coal workers' pneumoconiosis (black lung) with pulmonary fibrosis (scarring of the lung).

  • 0 views
  • 25 Jan, 2021
  • 1 location
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Safety of Sildenafil in Premature Infants

Describe the safety of sildenafil in premature infants at risk of bronchopulmonary dysplasia and determine preliminary effectiveness and pharmacokinetics (PK) of sildenafil. Funding Source - FDA OOPD.

prematurity
premature birth
intermittent positive pressure ventilation
  • 18 views
  • 14 Nov, 2021
  • 21 locations
None
BPD Saturation TARgeting

Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, affects nearly half of extremely preterm infants.This study evaluates the use of supplemental oxygen to manage infants with established BPD. Participants will be randomly placed in either a higher oxygen saturation group or a lower oxygen saturation target group.

premature birth
severe bronchopulmonary dysplasia
pulmonary disease
chronic lung disease
prematurity
  • 0 views
  • 24 May, 2021
  • 3 locations
None
Multiparametric Bronchopulmonary Prediction

INTRODUCTION: Current Neonatology has failed to reduce the incidence of moderate-severe bronchopulmonary dysplasia (BPD). Although multiple models for predicting the risk of dysplasia in preterm infants have been studied, none have been implemented in clinical practice. OBJECTIVE: To calculate a mathematical model to predict moderate-severe bronchopulmonary dysplasia in newborns before …

  • 0 views
  • 19 Mar, 2021
  • 1 location
None
Influence of Respiratory Rate Settings on CO2 Levels During Nasal Intermittent Positive Pressure Ventilation (NIPPV).

Infants will be monitored by TcCO2 during three consecutive time periods of one hour each on a high and low rate of NIPPV, when in a stable condition. NIPPV rate will start high/low, changed to low/high and switched back to starting rate.

  • 0 views
  • 18 Apr, 2021
  • 1 location
None
TCM for Coal Worker's Pneumoconiosis

This study aims to evaluate the clinical efficacy of traditional Chinese medicine in the treatment of pneumoconiosis and to provide high-quality evidence for the prevention and treatment of pneumoconiosis.

  • 0 views
  • 20 Apr, 2021
  • 1 location
None
Indoor Air Quality and Respiratory Morbidity in School-Aged Children With BPD

Investigators want to learn the role of indoor environmental exposures on respiratory symptoms, and, separately, on lung function deficits in school-aged children with bronchopulmonary dysplasia (BPD).

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia

This is a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study of sildenafil in premature infants (inpatient in Neonatal Intensive Care Units (NICUs)) with severe bronchopulmonary dysplasia (BPD).

  • 0 views
  • 18 Jun, 2021
  • 1 location