Lung Injury Clinical Trials

A listing of Lung Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 14 clinical trials
A Phase II Study in Patients With Moderate to Severe ARDS Due to COVID-19

This is a Phase II multi-center, double-blind, placebo-controlled, randomized study in Patients with moderate to severe lung injury due to COVID-19 or other potential viral and bacterial

  • 0 views
  • 04 Aug, 2021
  • 2 locations
Study on the Use of Sarilumab in Patients With COVID-19 Infection

Sarilumab is an anti-interleukin-6 human monoclonal antibody, such as tocilizumab, which is administered subcutaneously every two weeks for the treatment of moderate to severe active rheumatoid arthritis in adult patients. Despite the effectiveness reported for tocilizumab in the recently published experiences, the need to rapidly find alternative therapies to manage …

  • 0 views
  • 26 Jul, 2021
  • 1 location
Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19)

This is a multicenter randomized controlled clinical trial with an adaptive design assessing the efficacy of setting the ventilator based on measurements of respiratory mechanics (recruitability and effort) to reduce Day 60 mortality in patients with acute respiratory distress syndrome (ARDS). The CAVIARDS study is also a basket trial; a …

positive end expiratory pressure
mechanical ventilation
FIO2
covid-19
assisted breathing
  • 0 views
  • 23 Jul, 2021
  • 23 locations
Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy, and lung injury affects as many as 25% of children receiving HSCT. Improved transplant techniques and major

  • 0 views
  • 26 Jul, 2021
  • 1 location
Low Frequency Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO

The acute respiratory distress syndrome (ARDS) is the most severe form of respiratory failure, presented in 10% of all intensive care patients and carrying a high mortality rate. Extracorporeal membrane oxygenation (ECMO) is a rescue treatment for patients with severe ARDS. Mechanical ventilator settings in patients with severe ARDS during …

FIO2
assisted breathing
respiratory distress
pao2
respiratory failure
  • 17 views
  • 04 Aug, 2021
  • 1 location
Early Use of Prone Position in ECMO for Severe ARDS

Extracorporeal membrane oxygenation (ECMO) is widely used in the salvage treatment of critical acute respiratory distress syndrome (ARDS). However, reduce lung injury, accelerate lung recovery

mechanical ventilation
FIO2
assisted breathing
ventilator-induced lung injury
pao2
  • 2 views
  • 28 Jul, 2021
  • 1 location
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome

Pulmonary distension induced by mechanical ventilation physiologically alters right ventricle pre and after-load, hence might lead to right ventricle failure. The hypothesis is that in Acute Respiratory Distress Syndrome, the occurence of a right ventricle failure under lung protective ventilation might : i) be correlated to the transpulmonary pressure level, …

mechanical ventilation
assisted breathing
acute lung injury
acute respiratory distress
positive end expiratory pressure
  • 0 views
  • 24 Jul, 2021
  • 2 locations
Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Patients

The two-part phases will each have a unique patient population, The goal in this application is to see if that carotid bodies are "offline" is correct and to determine whether a cohort of SARS-Cov-2 patients can be identified who fit this profile and would be suitable for drug treatment. The …

  • 0 views
  • 23 Jul, 2021
  • 1 location
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation

Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put

graft dysfunction
  • 0 views
  • 21 Jul, 2021
  • 1 location
Study of Lung Proteins in Patients With Pneumonia

This study will examine the different types of proteins present in the lungs of patients with pneumonia to explore the causes of different types of the disease. Pneumonia is a condition that causes lung inflammation AND is often caused by an infection. It is usually diagnosed by lung x-rays and …

withdrawn
x-rays
pneumonia
bronchoscopy
lidocaine
  • 29 views
  • 04 Aug, 2021
  • 1 location