Cutaneous T-Cell Lymphoma Clinical Trials

A listing of Cutaneous T-Cell Lymphoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 51 clinical trials
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis Fungoides

This phase II trial studies how well ultra low dose radiation therapy works in treating patients with mycosis fungoides. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Giving ultra low doses of radiation may help control the disease and reduce side effects compared to treatment …

mycosis
tumor cells
serum pregnancy test
low dose radiation therapy
measurable disease
  • 277 views
  • 25 May, 2022
  • 1 location
Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungoides

This phase Ib/II trial investigates the side effects of mogamulizumab and extracorporeal photopheresis and to see how well they work in treating patients with Sezary syndrome or mycosis fungoides. Mogamulizumab (a humanized antibody) binds to CCR4, a protein often found in high amounts on T-cell lymphoma cells. Binding to these …

bilateral oophorectomy
neutrophil count
chemotherapy regimen
lymphoma
systemic therapy
  • 0 views
  • 10 Jul, 2022
  • 1 location
Pembrolizumab in Combination With Gemcitabine in People With Advanced Mycosis Fungoides or Sézary Syndrome

The purpose of this study is to find out whether the combination of pembrolizumab and gemcitabine is an effective treatment for mycosis fungoides and Sézary syndrome.

cancer therapy
erythropoietin
adrenal insufficiency
neutrophil count
direct bilirubin
  • 0 views
  • 07 Jul, 2022
  • 7 locations
Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

safety, tolerability and the pharmacokinetics/pharmacodynamics (PK/PD) of KT-333 in Peripheral T-cell Lymphoma (PTCL), Cutaneous T-Cell Lymphoma (CTCL), Large Granular Lymphocytic Leukemia (LGL-L), and

t-cell lymphoma
cutaneous t-cell lymphoma
solid tumor
measurable disease
lymphoma
  • 0 views
  • 29 Jul, 2022
  • 5 locations
MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal Photochemotherapy (MORPHEE)

The objective of this study is to describe the type of cell death induced by extracorporeal photochemotherapy, depending on the cell type, using a panel of complementary analysis techniques.

lymphoma
puva
extracorporeal photopheresis
cutaneous t-cell lymphoma
  • 0 views
  • 18 Jun, 2022
  • 1 location
Romidepsin Maintenance After Allogeneic Stem Cell Transplantation

stem cell transplant will also be studied. This is an investigational study. Romidepsin is FDA approved and commercially available for the treatment of CTCL in patients who have received at

renal function
t-cell lymphoma
cutaneous t-cell lymphoma
lymphoid leukemia
romidepsin
  • 122 views
  • 03 May, 2022
  • 1 location
A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-cell Malignancies

Background Mature T-cell malignancies (TCMs) are a rare group of cancers that usually do not have effective treatments or cures. Because of this, participants with TCMs often relapse and have a poor overall prognosis. This trial is testing if combining several drugs against TCMs can be a more effective. Primary …

revlimid
cc-486
cutaneous t-cell lymphoma
neutrophil count
dexamethasone
  • 0 views
  • 18 Sep, 2022
  • 1 location
Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

This randomized phase I/II trial studies the best dose and side effects of durvalumab and to see how well it works with or without lenalidomide in treating patients with cutaneous or peripheral T cell lymphoma that has come back and does not respond to treatment. Monoclonal antibodies, such as durvalumab, …

monoclonal protein
serum pregnancy test
cutaneous t-cell lymphoma
neutrophil count
anticoagulants
  • 64 views
  • 25 Mar, 2022
  • 1 location
Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

This phase II trial studies how well letermovir works for the prevention of cytomegalovirus reactivation in patients with hematological malignancies treated with alemtuzumab. Patients receiving treatment with alemtuzumab may experience cytomegalovirus reactivation. Letermovir may block cytomegalovirus replication and prevent infection.

  • 0 views
  • 15 Mar, 2021
  • 1 location
Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

This phase II trial studies how well pembrolizumab works in treating patients with stage IB-IV mycosis fungoides. Antibodies, such as pembrolizumab, may interfere with the ability of cancer cells to grow and spread.

cancer
erythropoietin
mycosis
metastatic tumor
serum pregnancy test
  • 9 views
  • 10 Apr, 2022
  • 1 location