Wilson's Disease Clinical Trials

A listing of Wilson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 25 clinical trials
Myo-inositol for the Management of Poor Ovarian Responders: A Prospective Randomized Controlled Trial

The management of poor ovarian responders (POR) remains the most challenging in In-Vitro Fertilization (IVF). The incidence of POR ranges between 9 and 24% (Caprio F, et al, 2015). POR refers to a reduction in the quantity of primordial follicle pool in reproductive age group (Jirge, P. R., 2016, Sunkara, …

  • 66 views
  • 27 Feb, 2022
  • 1 location
Study of ALXN1840 Versus Standard of Care in Pediatric Participants With Wilson Disease

This study is being conducted to evaluate the efficacy, safety, pharmacokinetics (PK), and pharmacodynamics of ALXN1840 versus standard of care in pediatric participants with Wilson disease (WD

copper
trientine
zinc
penicillamine
  • 0 views
  • 17 Jun, 2022
  • 18 locations
The Individual Therapy for Patients With Wilson's Disease

Based on the genotype characteristics and genotype-phenotype-treatment prognosis data of Chinese WD patients, this study intends to further optimize the treatment regimen of Chinese WD patients

dmsa
dmps
zinc
penicillamine
  • 207 views
  • 09 Feb, 2022
  • 1 location
Description of the Copper Concentration in Breast Milk in Women Treated for Wilson's Disease (WILLACT)

Wilson's disease is a rare genetic disease, affecting less than 1,500 people in France. The transmission is autosomal recessive linked to an anomaly of the ATP7B gene on chromosome.This gene

copper
trientine
zinc
liver transplant
atp7b gene
  • 0 views
  • 07 Oct, 2022
  • 1 location
A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease (GATEWAY)

intravenously (IV) to adult patients with Wilson's Disease prior to and following background WD therapy withdrawal.

atp7b gene
copper
ceruloplasmin
  • 33 views
  • 04 Oct, 2022
  • 5 locations
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Seamless, Adaptive, Safety, Dose-Finding, and Phase 3 Clinical Study of UX701 AAV-Mediated Gene Transfer for the Treatment of Wilson Disease

The primary objectives of this study are to evaluate the safety of single IV doses of UX701 in patients with Wilson disease, to select the UX701 dose with the best benefit/risk profile based on

copper
trientine
zinc
penicillamine
  • 4 views
  • 14 Oct, 2022
  • 12 locations
Establishment of a Prospective Clinical-biological Database

A Clinical and Biological Database will provide to the scientific community a collection of blood and tissues with clinical data to improve knowledge about cancer and help to develope new cancer treatments. This database is specific to Sarcoma

cancer
  • 0 views
  • 14 Nov, 2021
  • 1 location
Acute Effects of Added Sugar Intake on Cerebrovascular Function and Brain Integrity

This study will focus on acute effects of added sugars on brain health in a specific age group (30-64 years old). We will provide participants two meals (one meal containing 16 g of added sugars and the other containing 61 g of added sugars) and examine blood vessel function and …

Accepts healthy volunteers
  • 0 views
  • 17 Jun, 2022
  • 1 location
The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy

This research study has been designed to test whether a drug called trientine dihydrochloride (also called Cufence) reduces heart muscle thickening, improves exercise capacity, improves heart function and reduces abnormal heart rhythms in patients with hypertrophic cardiomyopathy (HCM). The study is also assessing how trientine works in HCM. Participants will …

  • 0 views
  • 26 Mar, 2021
  • 4 locations
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas

The main objective of this project is to identify a new non-invasive biological test for the diagnosis of LPS by measuring circulating serine levels. The current gold standard is the detection of Mdm2 amplification by the FISH.

  • 0 views
  • 26 Jan, 2021
  • 1 location