Idiopathic Pulmonary Fibrosis Clinical Trials

A listing of Idiopathic Pulmonary Fibrosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 245 clinical trials
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Low-Dose Danazol for the Treatment of Telomere Related Diseases

Background DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes can develop diseases of the bone marrow, lung, and liver. Researchers want to …

  • 57 views
  • 10 Oct, 2021
  • 1 location
None
Hyperpolarized Xenon-129 MR Imaging of the Lung

Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial and vascular dysfunction, and to cause murine phenotypes similar to those of human COPD. Recently, "spiked" vape juice has been linked …

  • 2 views
  • 26 Jan, 2021
  • 1 location
None
Sputum Microbiota and the Association With Clinical Parameters in Steady-state Acute Exacerbation and Convalescence of Bronchiectasis

Study 1 is a cross-sectional investigation. Patients with clinically stable bronchiectasis (symptoms, including cough frequency, sputum volume and purulence, within normal daily variations) will undergo baseline assessment consisting of history taking, routine sputum culture, 16srRNA pyrosequencing, measurement of sputum inflammatory markers, oxidative stress biomarkers and MMPs, and spirometry. Microbiota taxa …

antibiotic therapy
grip
spirometry
cough
antibiotics
  • 27 views
  • 23 Jan, 2021
  • 1 location
None
Abatacept Bone Effects in Psoriatic Arthritis With Bone Biomarker

Observation has pointed out, that osteitis present in the MRI scans, predicts bone erosion and that this in accordance with the concept by underlining the importance of bone marrow involvement in arthritis [Krabben A, 2013]. Abatacept with its favourable safety profile preferentially interrupts activation of nave T cells and perhaps …

  • 2 views
  • 24 Jan, 2021
None
Thymalfasin (Thymosin Alpha 1) to Treat COVID-19 Infection

It is our hypothesis that a course of Ta1 administered to hospitalized individuals with COVID-19 infection and lymphocytopenia will improve the time to recovery (primary objective) and severity of infection (secondary objectives) compared to untreated individuals in the same hospital with comparable lymphocytopenia. After screening, hospitalized patients with COVID-19 and …

lymphopenia
  • 0 views
  • 26 Sep, 2021
  • 1 location
None
Zephyrus II: Efficacy and Safety Study of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis (IPF). There is a 48-week randomized treatment phase followed by an optional, open-label extension phase.

pirfenidone
nintedanib
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
carbon monoxide
  • 3 views
  • 14 Nov, 2021
  • 122 locations
None
A Study to Test the Efficacy and Safety of Inhaled GB0139 in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

This is a randomized, double-blind, placebo-controlled phase 2b trial in subjects with IPF (idiopathic pulmonary fibrosis) investigating the efficacy and safety of GB0139.

pirfenidone
nintedanib
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
carbon monoxide
  • 385 views
  • 27 Aug, 2021
  • 142 locations
None
Safety Efficacy and Pharmacokinetics of C21 in Subjects With IPF

This trial is a multi-centre, open-label, single-arm phase 2 trial investigating the safety, efficacy and pharmacokinetics of C21 in subjects with idiopathic pulmonary fibrosis.

idiopathic pulmonary fibrosis
emphysema
  • 0 views
  • 06 Oct, 2021
  • 21 locations
None
Evaluation of Efficacy and Safety of PLN-74809 in Patients With Idiopathic Pulmonary Fibrosis

participants with idiopathic pulmonary fibrosis.

pirfenidone
nintedanib
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
  • 20 views
  • 26 Aug, 2021
  • 31 locations
None
Evaluation of Efficacy and Safety of Pamrevlumab in Patients With Idiopathic Pulmonary Fibrosis

Pulmonary Fibrosis

pirfenidone
nintedanib
diffusion capacity of the lung for carbon monoxide
idiopathic pulmonary fibrosis
carbon monoxide
  • 374 views
  • 11 Nov, 2021
  • 228 locations