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Crohn's Disease Clinical Trials

A listing of Crohn's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (74) clinical trials

MRI Differentiating Gut TB and Crohn's

The clinical presentation of gut tuberculosis and Crohn's disease is very similar. In areas endemic of tuberculosis infection, differentiating the two diseases remains difficult. Both disease entities can have similar clinical, endoscopic and histological findings. Yet, wrongly diagnosing gut tuberculosis as Crohn's disease can potentially result in disastrous outcomes, especially ...

Phase N/A

COmparison of MicroBiota AccordIng to Age in Crohn's Disease (COMeBACk)

The primary aim is to describe by principal component analysis and compare the gut microbiota between subgroups of paediatric-onset (n=75), elderly-onset CD patients (n=75) and control subjects (75 paediatric control and 75 elderly control subjects matched on age) without an a priori approach of high throughput sequencing of bacterial DNA. ...

Phase N/A

Predictive Factors of Clinical Response to Ustekinumab in Active Crohn's Disease

Ustekinumab is a fully human Immune Globulin Gk (IgGk) monoclonal antibody against the common p40 subunit of interleukin-12 and interleukin-23, which are implicated in the pathogenesis of inflammatory bowel disease. Its efficiency to induce and maintain clinical response in patients with anti TNF resistant Crohn's disease has been proved in ...

Phase N/A

Fecal Calprotectin Collection Protocol

Stools will be collected and tested, at a later date, in a clinical performance study with an investigational Calprotectin assay. This study will be coordinated by the Sponsor.

Phase N/A

Proteomic Analysis of Crohn's Disease Macrophages in Response or Not to AIEC

The macrophages characterization will be realized at a basal state and in response or not to AIEC. Investigator aimed to 1) better understand the differences between macrophages of CD patients, UC patients and healthy volunteers but also the impact of AIEC infection on these macrophages to provide key informations to ...

Phase N/A

Multimodal Approach in IBD Patients

Patients with a confirmed diagnosis of IBD will be prospectively assessed on a yearly basis in order to assess relapse risk factors. Disease activity will be assessed using the Mayo score for UC patients and CDAI for Crohn's disease and endoscopic activity will be assessed using the Mayo endoscopic subscore ...

Phase N/A

Canadian Children Inflammatory Bowel Disease Network (CIDsCANN)

The National Coordinating Centre has established and maintains an encrypted Network Website that will serve as the central portal for all Network communication and data transfer. All data related to the Network is stored within a single secure data repository facility which incorporates a state-of-the-art bio-repository sample tracking system, as ...

Phase N/A

Comprehensive DNA Methylation Profiling in Crohn's Disease

Previous studies have indicated that abnormal DNA methylation frequently occurs in the mucosa in Crohn's disease. Comprehensive DNA methylation profiling of the inflamed and non-inflamed ileal mucosa of patients with Crohn's disease was performed. Genome-wide DNA methylation was determined using the Illumina HumanMethylation 850k BeadChip.

Phase N/A

Inflammatory Bowel Disease in South Eastern Norway

The IBSEN III study will investigate the incidence of inflammatory bowel disease in South Eastern Norway and describe the clinical course of the disease. The investigators will map newly diagnosed and treatment naive IBD patients at various levels (epidemiological, clinical, psychosocial and nutritional as well as immunological, genetic, epigenetic and ...

Phase N/A

Surgically Resected Crohn's Disease Patients: Prognostic Factors for Re-operation and New Score Building

Patients will be consecutively enrolled in this prospective cross-sectional study, during the first 12 months, and then followed for 12 (minimum) up to 24(maximum) months, depending on date of patients' enrolment (total study length: 2 years). Patients will be stratified according to risk factors and type of treatment carried out ...

Phase N/A