Crohn's Disease Clinical Trials

A listing of Crohn's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 321 clinical trials
Effect of Ileocolonic Delivered Vitamins and an Anti-Inflammatory Diet on Crohn's Disease and Healthy Volunteers (Vita-GrAID)

This study will evaluate if the Groningen Anti-Inflammatory Diet and the ileocolonic delivery of vitamin B2, B3 and C can positively influence the course of Crohn's disease and can positively

vitamin
faecal calprotectin
crohn's disease
mucosal inflammation
Accepts healthy volunteers
  • 0 views
  • 11 Aug, 2022
  • 1 location
A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease

A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present. The main aim of this study is to learn if complex perianal fistulas in children …

methotrexate
luminal
mercaptopurine
ulceration
crohn's disease
  • 0 views
  • 27 Oct, 2021
  • 23 locations
A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

This is an extension study to evaluate safety and efficacy of ozanimod in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
  • 1128 views
  • 22 Sep, 2022
  • 492 locations
Study to Assess Efficacy and Safety of Cx601 Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Participants With Crohn's Disease (CD)

The purpose of this study is to evaluate the combined remission of complex perianal fistulas, defined as the clinical assessment at Week 24 of closure of all treated external openings that were draining at baseline despite gentle finger compression, and absence of collections greater than (>) 2 centimeter (cm) (in …

methotrexate
luminal
immunosuppressive agents
tumour necrosis
endoscopy
  • 236 views
  • 02 Dec, 2021
  • 178 locations
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.

tumour necrosis
ileitis
tumor necrosis factor
ileocolitis
tumor necrosis factor alpha
  • 14 views
  • 14 Apr, 2022
  • 12 locations
  • 0 views
  • 19 Aug, 2022
  • 42 locations
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

abdominal pain
crohn's disease
remission
  • 992 views
  • 16 Sep, 2022
  • 482 locations
Induction Study #2 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

ileal disease
abdominal pain
corticosteroids
endoscopy
immunomodulators
  • 550 views
  • 16 Sep, 2022
  • 354 locations
Induction Study #1 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

ileal disease
abdominal pain
corticosteroids
endoscopy
immunomodulators
  • 918 views
  • 20 Sep, 2022
  • 387 locations
A Phase 2/3, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group, Multicenter Protocol to Evaluate the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease (GALAXI)

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease

ileitis
endoscopy
ileocolitis
crohn's disease
colitis
  • 861 views
  • 21 Sep, 2022
  • 492 locations