Crohn's Disease Clinical Trials

A listing of Crohn's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 250 clinical trials
A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease

A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present. The main aim of this study is to learn if complex perianal fistulas in children …

crohn's disease
luminal
azathioprine
monoclonal antibodies
mercaptopurine
  • 0 views
  • 27 Aug, 2023
  • 22 locations
Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

crohn's disease
endoscopy
ileal disease
abdominal pain
immunomodulators
  • 918 views
  • 03 Sep, 2023
  • 188 locations
Induction Study #2 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

This is a study to explore the effect of oral ozanimod as an induction treatment for participants with moderately to severely active Crohn's Disease.

crohn's disease
ileal disease
abdominal pain
corticosteroids
endoscopy
  • 566 views
  • 09 Sep, 2023
  • 203 locations
A Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

This is a study to demonstrate the effect of oral ozanimod as maintenance therapy in participants with moderately to severely active Crohn's Disease.

crohn's disease
remission
abdominal pain
  • 1049 views
  • 11 Sep, 2023
  • 428 locations
A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease (DUET-CD)

The purpose of this study is to evaluate the efficacy of JNJ-78934804 at Week 48 compared to guselkumab and golimumab.

abdominal pain
combination therapy
crohn's disease
golimumab
  • 4 views
  • 19 Sep, 2023
  • 283 locations
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON) (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172

crohn's disease
ulcerative colitis
colitis
mirikizumab
ulceration
  • 2 views
  • 12 Aug, 2023
  • 10 locations
A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease (CULTIVATE)

active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics). The overall duration of this study is

biosimilar
azathioprine
mercaptopurine
tumor necrosis factor alpha
adalimumab
  • 209 views
  • 13 Sep, 2023
  • 344 locations
Study of the Kono-S Anastomosis Versus the Side-to-side Functional End Anastomosis

with Crohn's ileitis or Crohn's ileocolitis requiring resection will be randomized to undergo either the Kono-S anastomosis or the side-to-side functional end anastomosis.

ileocolitis
tumour necrosis
ileitis
tumor necrosis factor alpha
tumor necrosis factor
  • 14 views
  • 11 Apr, 2023
  • 8 locations
ENhanced Recovery in CHildren Undergoing Surgery (ENRICH-US)

The institution of perioperative Enhanced Recovery Protocols (ERPs) has been found to decrease hospital length of stay, in-hospital costs, and complications among adult surgical populations but data in pediatric populations are lacking. The Assessing Effectiveness and Implementation of a Perioperative Enhanced Recovery Protocol for Children Undergoing Gastrointestinal Surgery, which has …

crohn's disease
ulcerative colitis
colitis
inflammatory bowel disease
Accepts healthy volunteers
  • 0 views
  • 12 May, 2022
  • 1 location
A Long-term Extension Study of Ustekinumab in Pediatric Participants (UNITED)

The purpose of this study is to collect long-term safety data of subcutaneous (SC) ustekinumab

ustekinumab
remission
  • 0 views
  • 16 Sep, 2023
  • 22 locations