Colon Cancer Screening Clinical Trials

A listing of Colon Cancer Screening medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 591 clinical trials
Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia (ACCSIS)

This project aims to implement a multi-level group randomized trial, delayed intervention that includes components targeting clinics, providers, patients, and the community to increase colorectal cancer (CRC) screening, follow-up, and referral-to-care among patients age 50-74 in 12 counties in Appalachian Kentucky and Ohio. The 12 counties will be assigned to …

Accepts healthy volunteers
cancer screening
screening for colorectal cancer
  • 0 views
  • 27 May, 2022
  • 2 locations
Efficacy of HIPEC in Patients With Colorectal Cancer at High Risk of Peritoneal Carcinomatosis

The purpose of this study is to determine the efficacy of adjuvant HIPEC with Mitomycin C after colectomy in the treatment of colorectal cancer patients at high risk of peritoneal carcinomatosis.

mitomycin
adenocarcinoma
colorectal adenocarcinoma
hyperthermic intraperitoneal chemotherapy
systemic chemotherapy
  • 15 views
  • 25 Jan, 2021
  • 33 locations
mFOLFOXIRI Versus mFOLFOX6 as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer (FANTASTIC)

The current standard treatment for locally advanced rectal cancer is still fluorouracil-based neoadjuvant radiotherapy and chemotherapy followed by TME surgery, followed by adjuvant chemotherapy. Fluorouracil single-agent simultaneous sensitization of radiotherapy and chemotherapy has a pCR of about 15-20% and a tumor downgrade (ypStage 0-I) rate of about 35%. However, about …

metastasis
colon cancer
adjuvant therapy
fluorouracil
cancer surgery
  • 0 views
  • 04 Mar, 2022
  • 1 location
An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

The purpose of this study is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer of the colon or rectum that has spread.

nivolumab
metastatic colorectal cancer
colon cancer
  • 278 views
  • 28 Jun, 2022
  • 36 locations
Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

From the patients' perspective, the most formidable part of the colonoscopy experience is the process of bowel cleansing. A poorly tolerated bowel preparation regimen often leads to incompletion of scheduled colonoscopies which in turn undermines the effectiveness of colonoscopy, increases cost, and decreases patient satisfaction. The current standard bowel preparation …

bowel preparation
  • 63 views
  • 28 Feb, 2022
  • 1 location
Adjuvant Low Dose Aspirin in Colorectal Cancer (ALASCCA)

ALASCCA is a randomized, parallel group, double blind, multicenter, placebo-controlled, biomarker-based study of adjuvant treatment with low dose aspirin in patients with colorectal cancer. Hypothesis is that patients diagnosed with colorectal cancer and somatic mutations in PI3K pathway can significantly improve survival if treated with low dose aspirin.

aspirin
rectal carcinoma
  • 29 views
  • 03 May, 2022
  • 32 locations
Aspirin for Prevention of Postsurgical Recurrence and Metastasis in Asian Colorectal Cancer Patients: a Multi-center Randomized Trial

Background: Evidence of high quality has suggested that acetylsalicylic acid (ASA)/aspirin effectively reduces colorectal adenoma incidence and recurrence rate, and several randomized controlled trials (RCTs) strongly indicate its potential to prevent colorectal cancer (CRC) initiation and progression and to decrease cancer-related mortality. However the role of aspirin supplied as an …

platelet count
anticoagulants
metastasis
aspirin
adenoma
  • 13 views
  • 21 Jan, 2021
  • 1 location
Scaling Colorectal Cancer Screening Through Outreach, Referral, and Engagement (SCORE): A State-Level Program to Reduce Colorectal Cancer Burden in Vulnerable Populations (SCORE)

This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75. We are implementing this study in two age groups, 45-49 years and 50-75 years.

fecal immunochemical test
adenoma
blood test
Accepts healthy volunteers
  • 0 views
  • 18 Sep, 2022
  • 1 location
Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis (CANWATCH)

Adjuvant chemotherapy was unnecessary in pathological stage Ⅱ colorectal cancer following initial treatment of surgery without high risk factors of recurrences. The treatment efficacy of adjuvant chemotherapy for pT1-3N0M0 colorectal cancer following preoperational chemotherapy or chemoradiotherapy remains unclear. Part of clinical local advanced colorectal cancer(cTxN1-2M0), which turn out to be …

adenocarcinoma
adjuvant chemotherapy
cancer
chemotherapy regimen
  • 0 views
  • 21 Mar, 2022
  • 1 location
Anesthesia and Cancer Study: Colon Cancer

This study investigates the influence of type of anesthesia on survival and recurrence rate in patients receiving colon cancer surgery. The participants will be allocated to either the TIVA group and the inhalation group.

cancer surgery
induction of anesthesia
sevoflurane
cancer
propofol
  • 394 views
  • 12 May, 2022
  • 2 locations