Colon Cancer Screening Clinical Trials

A listing of Colon Cancer Screening medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 66 clinical trials
Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON)

Comparing different method of surgical technique D2 lymph node dissection vs D3 for right colon cancer.

adenocarcinoma
hemicolectomy
transverse colon cancer
  • 68 views
  • 19 Aug, 2022
  • 1 location
Neoadjuvant Immunotherapy in Rectal Cancer: A Pilot Study Examining the Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer

Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer mortality in the United States. The current standard of care (SOC) for locally advanced rectal cancer includes neoadjuvant chemotherapy and radiation followed by surgery. However, great variability exists in patient's response to neoadjuvant chemoradiotherapy …

adenocarcinoma
neutrophil count
pembrolizumab
chemoradiotherapy
adenocarcinoma of rectum
  • 0 views
  • 16 Sep, 2022
  • 1 location
Phase II Study to Assess the Safety of Non-operative Management for Low Rectal Cancer (NOM)

This is a 5 year Phase II study to evaluate the safety of non-operative management (NOM) in patients with low rectal cancer (LRC) who achieve a complete clinical response (cCR) following chemoradiotherapy (CRT). The safety of NOM will be evaluated by assessing (i) rate of local re-growth and (ii) rate …

fluorouracil
cancer
chemoradiotherapy
capecitabine
rectal carcinoma
  • 6 views
  • 21 Sep, 2022
  • 1 location
A Phase 1/2a Study to Evaluate the Dose, Safety and Tolerability and Efficacy of an Intraperitoneal α-emitting Radionuclide Therapy (Radspherin®) in Subjects With Peritoneal Carcinomatosis From Colorectal Carcinoma Following Hyperthermic Intraperitoneal Chemotherapy

This is a phase 1/2a open label study to evaluate the dose, safety, tolerability and efficacy of an IP α-emitting radionuclide therapy (Radspherin®) in subjects with peritoneal carcinomatosis (PC) from colorectal carcinoma following complete CRS (cytoreduction score CC-0) and HIPEC. The study consists of three different cohorts: Dose escalation cohorts …

carcinoma
hyperthermic intraperitoneal chemotherapy
neutrophil count
metastasis
  • 0 views
  • 21 Sep, 2022
  • 2 locations
PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence (PARERE)

The association of doublet chemotherapy (FOLFOX and FOLFIRI) and anti-EGFR-moAbs (panitumumab or cetuximab) is a standard option for the first-line treatment of unresectable RAS and BRAF wt mCRC patients, especially with left-sided primary tumour. In RAS wt mCRC patients refractory to chemotherapy and anti-EGFR naive, the standard treatment sequence is …

  • 0 views
  • 09 Aug, 2022
  • 1 location
Phase Ib/II Study of TAS-102 Plus Radiation Therapy for the Treatment of the Liver in Patients With Hepatic Metastases From Colorectal Cancer

This research study is studying a drug in combination with radiation therapy as a possible treatment for hepatic metastases from colorectal cancer. The interventions involved in this study are: Trifluridine (TAS-102) Radiation Therapy

liver metastasis
neutrophil count
metastasis
measurable disease
tas-102
  • 27 views
  • 14 Sep, 2022
Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk

Determine in the context of a controlled crossover diet-intervention trial the role of taurocholic acid metabolism by gut bacteria in African American subjects at elevated risk for colorectal cancer (CRC). Two isocaloric diets, an animal-based diet high in taurine and saturated fat (HT-HSAT) and a plant-based, low in taurine and …

colon cancer
Accepts healthy volunteers
  • 4 views
  • 19 Sep, 2022
  • 1 location
A Phase I, Open-Label, Dose-Escalation Study Of The Safety And Pharmacokinetics Of BLYG8824A Administered Intravenously In Patients With Locally Advanced Or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

solid tumour
irinotecan
metastatic colorectal cancer
fluoropyrimidine
monoclonal antibodies
  • 5 views
  • 21 Sep, 2022
  • 6 locations
Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal Cancers

Background Metastatic or refractory/recurrent small bowel and colorectal cancers cannot be cured and are often not helped by standard treatments. Researchers want to find better treatments by testing a combination of drugs. Objective To learn if a new combination of immunotherapy drugs can shrink tumors in people with advanced small …

adenocarcinoma
liver metastasis
colorectal adenocarcinoma
neutrophil count
metastasis
  • 0 views
  • 19 Sep, 2022
  • 1 location
Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery (SPECS)

To determine whether exercise and nutrition prehabilitation improves patient outcomes after cancer surgery

cancer surgery
  • 0 views
  • 09 Aug, 2022
  • 1 location