Colon Cancer Screening Clinical Trials

A listing of Colon Cancer Screening medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 22 clinical trials
IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting (IROCAS)

The trial is a phase III, multicenter, open-labeled randomized trial comparing the association 5-fluorouracil (5-FU), folinic acid, irinotecan and oxaliplatin (mFOLFIRINOX) versus oxaliplatin, folinic acid, 5-FU (mFOLFOX 6) chemotherapy protocols in patients with high-risk stage III colon cancer in the adjuvant setting.

  • 116 views
  • 08 Aug, 2022
  • 8 locations
Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors (innovaTV 207)

This trial will study tisotumab vedotin to find out whether it is an effective treatment for certain solid tumors and what side effects (unwanted effects) may occur. There are four parts to this study. In Part A, the treatment will be given to participants every 3 weeks (3-week cycles). In …

adenocarcinoma
gemcitabine
cancer
bevacizumab
carboplatin
  • 247 views
  • 11 Aug, 2022
  • 33 locations
A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity of selpercatinib (also known as LOXO-292) administered orally to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer (MTC) and other tumors with RET activation.

cancer
cfdna
RET
solid tumour
renal function
  • 1278 views
  • 10 Aug, 2022
  • 86 locations
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair. Drugs used in combination chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different …

adenocarcinoma
immunosuppressive
monoclonal antibodies
antifungal agents
colon cancer
  • 1145 views
  • 08 Aug, 2022
  • 546 locations
Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. Genetic tests look at the unique genetic …

taselisib
ulixertinib
luteinizing hormone
afatinib
dolutegravir
  • 6575 views
  • 08 Aug, 2022
  • 909 locations
Endoscopic Mucosal Resection Versus Endoscopic Submucosal Dissection for Colorectal Laterally Spreading Lesions. (intERsection)

EMR and ESD are both effective and safe and are associated with a very low risk of procedure related mortality when performed for colorectal laterally spreading lesions (LSL). Some kind of LSLs have a low risk of submucosal invasive carcinoma (SMIC) or these foci are found in well demarcated areas …

  • 0 views
  • 11 Aug, 2022
  • 1 location
Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON)

Comparing different method of surgical technique D2 lymph node dissection vs D3 for right colon cancer.

adenocarcinoma
hemicolectomy
transverse colon cancer
  • 68 views
  • 08 Aug, 2022
  • 1 location
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)

A phase Ib/II, open-label, multicenter, randomized study designed to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of immunotherapy-based treatment combinations in patients with metastatic colorectal cancer (mCRC) that became refractory to first- and second-line standard therapies. Eligible patients will be assigned to one of several treatment arms.

adenocarcinoma
fluoropyrimidine
metastatic colorectal cancer
bevacizumab
irinotecan
  • 70 views
  • 10 Aug, 2022
  • 8 locations
PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence (PARERE)

The association of doublet chemotherapy (FOLFOX and FOLFIRI) and anti-EGFR-moAbs (panitumumab or cetuximab) is a standard option for the first-line treatment of unresectable RAS and BRAF wt mCRC patients, especially with left-sided primary tumour. In RAS wt mCRC patients refractory to chemotherapy and anti-EGFR naive, the standard treatment sequence is …

  • 0 views
  • 09 Aug, 2022
  • 1 location
Clinical Trial Comparing Standard Care Versus Prehabilitation in Patients Undergoing Cancer Surgery (SPECS)

To determine whether exercise and nutrition prehabilitation improves patient outcomes after cancer surgery

cancer surgery
  • 0 views
  • 09 Aug, 2022
  • 1 location