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Breast Reconstruction Clinical Trials

A listing of Breast Reconstruction medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (32) clinical trials

Intraoperative Electron Beam Radiotherapy Boost in Treating Patients With Stage I-II Breast Cancer Undergoing Surgery With Reconstruction

PRIMARY OBJECTIVES: I. To determine the rate of grade 3 breast fibrosis at 1 year in women undergoing lumpectomy with oncoplastic reconstruction and immediate intraoperative electron radiotherapy boost followed by adjuvant whole breast radiotherapy. SECONDARY OBJECTIVES: I. To determine the rate of 5 year ipsilateral breast tumor recurrence rate. II. ...


PEC Block II in Mammoplasty Surgeries

Patients undergoing Breast Augmentation Mammoplasty were submitted to laryngeal mask placement after anesthetic induction with Fentanyl 3ucg/kg , Propofol 2mg/kg and Atracurium 0,5mg/kg and surgery was performed under standard surgical practices. Before the surgical incision patients were randomized either to receive a Bilateral Pectoralis Major Block(PEC I and II) with ...

Phase N/A

Depression and Body Image Distress Following Mastectomy With Reconstruction

Mastectomy is a major surgery that can have a profound effect on women's psychosocial wellbeing, including elevated depression and body image distress. Reconstructive breast surgery aims to improve patients' psychosocial adjustment to mastectomy, yet for some women substantial distress persists after reconstruction. However, very little is known about risk or ...

Phase N/A

The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction

Currently, there is level C evidence for the efficacy of Botox in the treatment of postoperative pain and muscle spasms in breast reconstruction patients. Additional high-level evidence is necessary to justify the use of Botox in breast cancer patients, which potentially will improve the reconstructive process for these patients and ...


Pilot Study for 3-Dimensional Surface Imaging in Implant-based Breast Reconstruction

Aim To test the feasibility of a number of novel initiatives prior to their use in a multi-centre study. The future study will develop a way to measure cosmetic outcome for implant-based breast reconstruction using 3-dimensional Surface Imaging (3D-SI). Methods At The Royal Marsden Hospital in Sutton 125 implant-based reconstructions ...

Phase N/A

Direct to Implant Breast Reconstruction Based Pre- or Retropectoral

Women diagnosed with breast cancer, large areas of ductal carcinoma in situ or a hereditary high risk of breast cancer are offered a mastectomy either as a therapeutic or a risk reducing intervention. Those, who are found eligible for an immediate breast reconstruction using an implant are reconstructed by either ...

Phase N/A

Clinical Trial With Two Physical Therapy Protocols After Breast Cancer Surgery and Immediate Reconstruction

Methods Patients will be recruited just after surgery scheduling. They will undergo preoperative evaluation one week before the surgery on average. At this moment, preoperative analysis will be conducted with personal data and medical history. Patients will undergo new assessments 07, 15, 30, 60, 90 and 180 days after surgery, ...

Phase N/A

Selective Intraoperative Administration of Local Anesthesia in Breast Reconstruction

One in eight women will develop breast cancer in her lifetime, and many of these women undergo mastectomy followed by breast reconstruction by insertion of a tissue expander below the pectoralis major muscle. Women undergoing breast reconstruction have been shown to have a significantly higher level of acute postoperative pain ...


A Comparison Between Biological (Veritas ) vs Non Biological Mesh (TIGR ) in Immediate Breast Reconstruction

The scientific evidence using different types of mesh in breast reconstruction is low at present with very few randomized controlled studies. This study aims to compare a biological mesh (Veritas) compared to a non biological mesh (TIGR) in patients with hereditary increased risk of developing breast cancer operated with bilateral ...

Phase N/A

Impact of Radiotherapy on Patients Undergoing DIEP Flap Breast Reconstruction

Since 1997, breast cancer has been the most common cancer in the UK, accounting for 31% of all new cancers in women. According to the latest statistics published by Cancer Research UK, approximately 50,000 women were diagnosed with breast cancer in 2010(1). In the UK, 53% of women with symptomatic ...

Phase N/A