High Blood Pressure (Hypertension - Pediatric) Clinical Trials

A listing of High Blood Pressure (Hypertension - Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 187 clinical trials
Heart Inflammation and Mental Stress Study (HIMS)

The aim of the study is to investigate the neural underpinnings of cardiovascular reactivity to mental stress as a function of HIV and hypertensive risk.

Accepts healthy volunteers
prehypertension
hypertension
  • 22 views
  • 10 Feb, 2022
  • 1 location
mGlide RCT: A Clinical Glide Path To Close the Guideline-to-Practice Gap In HTN Management

Hypertension (HTN) is the most important stroke and cardiovascular disease (CVD) risk factor. Unfortunately, there is substantial under-treatment of HTN. Of the 86 million adults with prevalent HTN in the U.S., 40 million (46%) have inadequately controlled blood pressure (BP). This problem is worse among minority groups. In this study, …

stroke
systolic blood pressure
hypertension
cardiovascular disease
  • 5 views
  • 03 Feb, 2022
  • 1 location
Controlling and Lowering Blood Pressure With the MobiusHD™ (CALM-DIEM)

To perform post-market surveillance and evaluate the performance of the MobiusHD System in subjects with primary resistant hypertension.

antihypertensive drugs
hypertension
resistant hypertension
  • 2 views
  • 13 Jun, 2022
  • 14 locations
Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate

An increasing number of studies have indicated that most fast food and common grocery items, contain large amount of inorganic phosphate-based food additives , which are highly absorbable. The long-term cardiovascular consequences of a high phosphate diet are unknown but the existing database implicates phosphate excess as an independent risk …

nephropathy
prehypertension
hypertension
  • 201 views
  • 09 Nov, 2021
  • 2 locations
Diet Intervention for Hypertension: Adaptation and Dissemination to Native Communities (NOSH)

We will conduct a randomized trial to test our DASH (Dietary Approaches to Stop Hypertension) based intervention in 370 adult American Indians with inadequately controlled systolic blood pressure (≥130 mmHg). Over the 5 years of the project, we will recruit and randomize 200 participants from each of 4 urban sites: …

nutrition education
systolic blood pressure
antihypertensive drugs
hypertension
diet, sodium-restricted
  • 55 views
  • 21 Jul, 2022
  • 1 location
Nesiritide in Hypertension

Hypertension remains a global burden in cardiovascular disease leading to stroke, myocardial infarction, and heart failure. Its myocardial complications result from increased mechanical load on the heart. Under physiological conditions of increased myocardial load and resulting myocardial stretch, atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) synthesis and secretion …

aldosterone
angiotensin
systolic blood pressure
renin
myocardial infarction
  • 6 views
  • 22 Jan, 2021
  • 3 locations
Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Chlorthalidone (CTD) may produce various metabolic disturbances, including hypokalemia, activation of Renin-Angiotensin- Aldosterone (RAA) system, oxidative stress, dyslipidemia, Fibroblast growth factor 23 (FGF23) synthesis, and magnesium depletion. These factors may interact with each other to contribute to the development of insulin resistances and metabolic syndrome. Smaller studies have suggested that …

aldosterone
angiotensin
thiazide
renin
metabolic syndrome
  • 24 views
  • 21 Mar, 2022
  • 3 locations
Study 1: Effect of Minocycline Treatment on Drug-Resistant Hypertensive Patients

Hypertension (HTN) is the single most prevalent risk factor for cardiovascular disease, diabetes, obesity and metabolic syndrome. Recent American Heart Association (AHA) statistics indicate that one-third of all adults in the United States of America suffer from HTN. Despite advances in life style modification and multi-drug therapies, 20-30% of all …

diabetes
cardiovascular disease
systolic blood pressure
metabolic syndrome
antihypertensive drugs
  • 41 views
  • 08 Jun, 2022
  • 1 location
Neural Mechanism of Aldosterone-induced Insulin Resistance

Patients with high aldosterone hormone have higher blood glucose than normal people. This study is being done to understand how aldosterone hormone affects the nerve activity that controls blood flow in the muscles and blood glucose. The information may be helpful in selecting blood pressure medications which can improve not …

essential hypertension
aldosterone
insulin resistance
insulin
Accepts healthy volunteers
  • 70 views
  • 06 Apr, 2022
  • 1 location
Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension

The purpose of this study is to better understand the role of the abdominal veins (splanchnic capacitance) and the sympathetic nervous system in human hypertension. The investigators will test the hypothesis that constriction of abdominal veins due to sympathetic activation contributes to human hypertension. Splanchnic capacitance will be assessed in …

hypertension
  • 41 views
  • 22 Aug, 2021
  • 1 location