High Blood Pressure (Hypertension - Pediatric) Clinical Trials

A listing of High Blood Pressure (Hypertension - Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 135 clinical trials
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to …

Accepts healthy volunteers
SARS
  • 2858 views
  • 04 Mar, 2022
  • 43 locations
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality

Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the extent and basis of treatment failure in different patient populations. The vast majority of drug registration …

Accepts healthy volunteers
  • 211 views
  • 26 Feb, 2022
  • 1 location
Hypertension Chronobiome

Hypertension is a common condition with a concomitant burden of stroke, kidney disease and myocardial infarction. Its prevalence in developed societies is increasing as they age, and in less developed countries, as their populations assume aspects of the Western diet and lifestyle. Nocturnal non-dipping hypertension (NDHT) - the failure of …

nephropathy
infarct
systolic blood pressure
hypertension
stroke
  • 23 views
  • 05 Mar, 2022
  • 1 location
Evaluation of Splenic Metabolic Activity With 18FDG-PET in Hypertension

The purpose of this study is to evaluate the splenic activation in hypertensive patients, as compared to normotensives, using FDG-PET/CT imaging. Moreover, the investigators will investigate whether the splenic metabolic activity relates to the expression of circulating inflammatory proteins (high-sensitivity C-reactive protein [hsCRP]), interleukin-1b (IL-1b), tumor necrosis factor-a (TNF-a) or …

infarct
hypertension
stroke
cancer
Accepts healthy volunteers
  • 3 views
  • 24 Apr, 2022
  • 1 location
BAROSTIM THERAPY™ In Resistant Hypertension

The purpose of this registry (NCT02880631) is to evaluate the effect of BAROSTIM THERAPY with the BAROSTIM NEO System in the commercial setting in subjects recently implanted under the CE-Marked indication for resistant hypertension.

systolic blood pressure
hypertensive medication
diuretics
resistant hypertension
hypertension
  • 22 views
  • 27 Jan, 2022
  • 14 locations
The Role of Gut Microbiota in Hypertension

Hypertension is the single most prevalent risk factor for heart diseases, heart failure, kidney failure and stroke. About 1 in 3 adults in the United States have hypertension. Approximately 28-30% of hypertensive patients suffer from resistant hypertension (RH). Inflammation has been implicated in the pathogenesis of the hypertension. Additional data …

uncontrolled hypertension
resistant hypertension
hypertension
stroke
systolic blood pressure
  • 80 views
  • 04 Jun, 2022
  • 1 location
Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

hypertension
periodontitis
chronic periodontitis
periodontal disease
  • 54 views
  • 04 Oct, 2022
  • 1 location
Metabolic and Bone Changes After Adjuvant Cancer Treatments in Early Non-metastatic Breast Cancer

Breast cancer is the most common cancer type in European women. Patients treated for early non-metastatic breast cancer comprise a growing group of survivors due to early diagnosis and improved treatment. Many of these survivors experience adverse effects such as decreased bone mineral density, derangement of metabolic markers (fat, glucose, …

hypertension
insulin
osteopenia
bone mineral density
diabetes
  • 9 views
  • 27 Feb, 2022
  • 1 location
Exploratory Next Generation Sequencing to Identify Causative Variants for Bevacizumab-Induced Hypertension From Breast Cancer Study E5103 Germline DNA Samples

This research trial studies whole exome sequencing in finding causative variants in germline deoxyribonucleic acid (DNA) samples from patients with hypertension receiving bevacizumab for breast cancer. Studying samples of germline DNA in the laboratory from patients with hypertension receiving bevacizumab for breast cancer may help doctors learn about changes that …

breast cancer
biomarker analysis
bevacizumab
cancer
  • 4 views
  • 22 Oct, 2022
  • 1 location
Epidural Spinal Cord Stimulation for Hypertension in Patients With Neuropathic Pain

The purpose of the ESCAPE Study is to determine the extent to which epidural spinal cord stimulation (SCS) reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension. We also aim to determine the extent to which higher baseline BP (i.e., hypertension) predicts reductions in pain …

  • 6 views
  • 03 Feb, 2021
  • 2 locations