High Blood Pressure (Hypertension - Pediatric) Clinical Trials

A listing of High Blood Pressure (Hypertension - Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 17 clinical trials
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The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

The objective of the RADIANCE II Pivotal study is to demonstrate the effectiveness and safety of the Paradise System in subjects with Stage 2 hypertension on 0-2 medications at the time of consent. Prior to randomization, subjects will be hypertensive in the absence of hypertension medication.

hypertension
angiography
antihypertensive drugs
renal angiogram
antihypertensive therapy
  • 877 views
  • 01 Aug, 2021
  • 83 locations
Comparison of Optimal Hypertension Regimens

High blood pressure (Hypertension) is extremely common and is a major cause of heart disease, kidney disease and stroke. One in three of the UK (United Kingdom) population will require treatment for hypertension at some point in their lives. A healthy lifestyle alone is often not enough to control blood …

nephropathy
antihypertensive drugs
amlodipine
stroke
combinations
  • 601 views
  • 01 Aug, 2021
  • 14 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

endothelin receptor antagonist
ralinepag
endothelin
diuretics
cardiopulmonary exercise testing
  • 0 views
  • 29 Jul, 2021
  • 31 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

angiotensin ii
endothelin receptor antagonist
diuretics
arginine
right heart catheterization
  • 5462 views
  • 26 Jul, 2021
  • 297 locations
TARGET BP I Clinical Trial

The TARGET BP I Trial is a randomized, blinded, multi-center, international, sham-procedure controlled trial, comparing renal denervation performed with the Peregrine System Kit in the treatment group to the sham control group (without renal denervation - no alcohol infusion). Subjects will be randomized in a 1:1 fashion to treatment versus …

angiography
KIT
antihypertensive drugs
blood pressure diastolic
renal angiogram
  • 31 views
  • 01 Aug, 2021
  • 4 locations
Mindfulness and Neural Cardiovascular Control in Humans

This study evaluates the impact of mindfulness-based stress reduction (MBSR) on sympathetic nerve activity and arterial stiffness. The investigator's central hypothesis is that MBSR will reduce sympathetic activity and arterial stiffness.

blood pressure diastolic
systolic blood pressure
  • 2 views
  • 31 Jul, 2021
  • 1 location
A Study to Assess the Safety Tolerability and Efficacy of IONIS-AGT-LRx in Hypertensive Participants With Uncontrolled Blood Pressure

The purpose of this study is to evaluate the effect of IONIS-AGT-LRx compared to placebo on systolic blood pressure (SBP) from baseline to Study Day 85 in uncontrolled hypertensive participants on 3 antihypertensive medications and to evaluate the effect of IONIS-AGT-LRx on SBP, diastolic blood pressure (DBP) and plasma angiotensinogen …

angiotensin ii
potassium
antihypertensive drugs
body mass index
blood pressure diastolic
  • 0 views
  • 01 Aug, 2021
  • 35 locations
A Study to Evaluate ALN-AGT01 in Patients With Hypertension

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) effects of subcutaneous (SC) ALN-AGT01 in participants with hypertension. The study will be conducted in 4 parts: Part A will be a single ascending dose (SAD) phase in hypertensive participants, Part B will be …

hypertension
irbesartan
body mass index
electrocardiogram
hypertensive medication
  • 370 views
  • 23 Jul, 2021
  • 4 locations
Acute Effect of Isometric Exercise on Blood Pressure in Hypertensive Patients

International recommendations advocate dynamic or isometric strength training as an adjunct to aerobic exercise. Due to a lack of consensus, this research addresses the acute effects of isometric exercises by handgrip or lower limb isometry as a hypotensive strategy in hypertensive adults.

  • 0 views
  • 01 Aug, 2021
  • 2 locations
Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans

Experimental data have shown that timing of sodium intake impacts diurnal patterns of sodium excretion. The purpose of this study is to test the hypothesis that the time of day for salt intake impacts (1) blood pressure rhythms and urinary sodium excretion and (2) circadian timing of factors responsible for …

hypertension
  • 0 views
  • 30 Jul, 2021
  • 1 location