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Coronary Artery Disease Clinical Trials

A listing of Coronary Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (711) clinical trials

A Genomic Approach for Clopidogrel in Caribbean Hispanics

Despite the substantial work in cardiovascular pharmacogenomics published over the past decade, a fundamental gap remains in understanding whether the genomic diversity of Caribbean Hispanics accounts for high inter-individual variability of clinical outcomes to preventive dual antiplatelet therapy (DAPT) with Clopidogrel. Caribbean Hispanics are disproportionately affected by cardio-metabolic disorders, but ...

Phase N/A

Genetic Polymorphism Contributing to the Variability of Clopidogrel Response in Patients With Coronary Artery Disease

In an observational study with cross-sectional analysis and prospective data collection, the investigators recruit patients with: >20 years old An established coronary artery disease defined by an episode of STelevation myocardial infarction, nonSTelevation acute coronary syndrome or stable angina An exposure to clopidogrel therapy (75 mg per day for at ...

Phase N/A

Perioperative Myocardial Ischemia: Troponin Monitoring Cost-effectiveness Insights Into Pathophysiology

The study consists of four sub studies Troponin monitoring implementation - Sub study A Preoperative and postoperative hs-cTnT threshold - Sub study B Economic analysis - Sub study C Advanced cardiac imaging case-control study - Sub study D Study A:To implement and evaluate a Troponin T monitoring program in patients ...

Phase N/A

Smartphone Delivered In-home Cardiopulmonary Rehabilitation

This project aims to determine if a smartphone-delivered cardiac rehabilitation (CR) program could show similar clinical outcomes to in-person programs at a low cost in a large population of patients. Investigators will also assess the feasibility of tailoring a virtual CR program to a small sample of COPD participants who ...

Phase N/A

Molecular Determinants of Coronaruy Artery Disease

The purpose of this study is to discover genes that may cause Coronary Artery Disease (CAD) or Arteriovenous Malformation (AVM). Many human diseases are inherited or passed from parent to child in families. These diseases occur because of damage to a gene(s), the genetic material that is also called DNA. ...

Phase N/A

Diagnostic Performance of Coronary CT Angiography With CT FFR in Kidney Transplantation Candidates

Transplantation is the therapy of choice for most patients with stage 5 chronic kidney disease (CKD) and end stage renal disease (ESRD). Kidney transplantation improves quality of life and overall survival rates. Cardiovascular disease is the most common complication and leading cause of death in the transplant population. In order ...

Phase N/A

Registry of Coronary Artery Ill Patients With Platelet Test Results

The Onassist Project is an assistance for cardiologists that establishes an individual risk of stent thrombosis for each patient based on: a functional approach (evaluation of the antiplatelet effect of the antiplatelet regimen by multiple tests) and a pharmacogenomic approach (genetic profile of response to antiplatelet agents) It provides advices ...

Phase N/A

Dynamic Stress Perfusion CT for Detection of Inducible Myocardial Ischemia

Rationale: Cardiac computed tomography (CT) provides accurate assessment of the coronary arteries and detects significant coronary stenosis with high diagnostic accuracy. However, the hemodynamic relevance of these stenotic lesion remains unclear, although highly relevant for clinical decision-making. Recent technical developments with third-generation dual-source CT allow to determine myocardial perfusion during ...

Phase N/A

Coronary Physiology and Its Relationship to Anatomy in Patients With Diabetes Mellitus

Background There is currently no data on invasive measurement of FFR, CFR and IMR in patients with diabetes mellitus. Studies such as RIPCORD has shown that using coronary angiography alone to guide revascularization strategy may be flawed in a significant proportion of patients. Patients with diabetes mellitus are more likely ...

Phase N/A

Wall Shear Stress and Neointimal Healing Following PCI in Angulated Coronary Vessels

The past two decades have registered major advances in cardiovascular medicine that have improved patients' survival and quality of life. One area of major research and innovation is the field of percutaneous coronary interventions (PCI), a non-surgical procedure used to treat a narrowed heart artery with stents. Stents are metallic ...

Phase N/A