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Coronary Artery Disease Clinical Trials
A listing of Coronary Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found (708) clinical trials
Hybrid Coronary Revascularization Trial
The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). There are no new or "experimental" procedures being tested ...
A Multicenter Feasibility Study of DyeVert Plus™ Contrast Reduction System Use to Reduce Contrast Media Volumes in Angiography Procedures Using Optical Coherence Tomography Dyevert
The purpose of this post-market feasibility study is to evaluate whether DyeVert Plus Contrast Reduction System use during standard angiography procedures involving the use of OCT result in contrast media (CM) volume savings without reducing image quality. The primary objective of this study is to evaluate the volume (percentage) of ...
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug- Eluting StEnts: The ECLIPSE Trial . The Device is The Diamondback 360® Coronary Orbital Atherectomy System (OAS) 1.25mm classic crown.
This is a prospective, randomized one to one (1:1), multi-center trial designed to evaluate vessel preparation with Orbital Atherectomy (OA) compared to conventional balloon angioplasty technique prior to stent implantation for the treatment of severely calcified coronary artery lesions.
A Post-approval Study of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
This study will observe the continued performance of the Medtronic Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System in a real-world more-comer population.
Physiological assessment of coronary stenosis following PCI
This is a study to assess the relationship between iFR and coronary stenosis. iFR safely and accurately quantifies stenosis severity in a wide range of lesions and may be helpful in assessing post PCI (percutaneous coronary intervention) physiology.
Randomized Comparison of the Clinical Outcome of Single versus Multiple Arterial Grafts: the ROMA Trial
The study objective is to determine if the use of two or more arterial grafts in coronary artery bypass surgery (CABG) compared to a single arterial graft is associated with improved survival. There is no "experimental" procedures being tested in this study. Cardiac surgeons use both arterial and vein grafts ...
COBRA PzF Stenting to Reduce the Duration of Triple Therapy in Patients Treated With Oral Anticoagulation Undergoing Percutaneous Coronary Intervention
The primary purpose of this study is to determine whether treatment with the Cobra PzF stent with 14 day Dual Anti-Platelet Therapy (DAPT) has a better safety profile compared to standard FDA approved Drug Eluting Stent plus 6-Month Dual Anti-Platelet Therapy in patients undergoing coronary intervention who also require oral ...
The HeartFlow ADVANCE Registry: Assessing Diagnostic Value of Noninvasive FFRCT in Coronary CarE
The objective of the HeartFlow ADVANCE Registry is to evaluate utility, clinical outcomes and resource utilization of FFRCT-guided evaluation in clinically stable, symptomatic patients with coronary artery disease (CAD) in order to further inform patients, health care providers, and other stakeholders about which technologies are most effective and efficient in ...
The Value of Fractional Flow Reserve Derived from Coronary CT Angiography and Myocardial CT Perfusion in the Triage of Low to Intermediate Risk Chest Pain Patients
The purpose of this study is to evaluate the incremental benefit of Fractional Flow Reserve (FFR) derived from Coronary Computed Tomographic Angiography (CCTA) (CT-FFR) compared to CCTA with or without stress testing, using invasive FFR as the gold standard for patients with obstructive disease (> 30% and < 90% stenosis). ...
Randomized Trial of Cobra PzF Stenting to Reduce Triple Therapy
The primary purpose of this study is to determine whether treatment with the Cobra PzF stent with 14 day Dual Anti-Platelet Therapy (DAPT) has a better safety profile compared to standard FDA approved Drug Eluting Stent plus 6-Month Dual Anti-Platelet Therapy in patients undergoing coronary intervention who also require oral ...