Coronary Artery Disease Clinical Trials

A listing of Coronary Artery Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 91 clinical trials
FFR Versus Angiography-Guided Strategy for Management of AMI With Multivessel Disease

The aim of the study is to compare clinical outcomes following fractional flow reserve (FFR)-guided versus angiography only guided strategy in treatment of non-infarction related artery (non-IRA) stenosis in patients with acute myocardial infarction (AMI) with multivessel disease Prospective, open-label, randomized, multicenter trial to test the clinical outcomes following FFR-guided …

ischemia
stenosis
q waves
bundle branch block
angiography
  • 0 views
  • 19 Sep, 2021
  • 2 locations
Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography

coronary angioplasty (Percutaneous coronary intervention, PCI) in patients with myocardial ischemia proved in myocardial scintigraphy.

  • 0 views
  • 05 Sep, 2021
  • 1 location
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD

The Ischemia-IMT (Ischemia-Intensive Medical Treatment Reduces Events in Women with Non-Obstructive CAD), subtitle: Women's Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR) trial

hmg-coa reductase inhibitors
coronary ct
rosuvastatin
angina pectoris
ischemia
  • 492 views
  • 19 Sep, 2021
  • 71 locations
The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

. Patients referred for isolated CABG for multi-vessel coronary artery disease and deemed technically suitable for sternotomy CABG as well as for MICS CABG are considered for enrollment into the trial

angina pectoris
bypass graft
arterial disease
  • 12 views
  • 19 Sep, 2021
  • 13 locations
PeRcutaneous cOronary Intervention of Native Coronary arTery Versus Venous Bypass Graft in Patients With Prior CABG

Multi-centre, randomised clinical trial with anticipated 17 European centres: in the Netherlands, Belgium, Germany and UK. Patients with a dysfunctional bypass graft with a clinical indication for revascularization will be randomized to either PCI of the native vessel or PCI of the dysfunctional venous bypass graft. 584 patients with a …

coronary disease
revascularisation
dapt
angiography
bypass graft
  • 0 views
  • 19 Sep, 2021
  • 20 locations
Functional Assessment by Virtual Online Reconstruction. The FAVOR III Europe Japan Study

Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is estimated based on two angiographic projections. Studies have shown a good correlation with the present wire-based standard approach Fractional Flow Reserve (FFR) for assessment of intermediate coronary stenosis. The purpose of the …

stable angina
stenosis
angina pectoris
angiography
coronary artery stenosis
  • 21 views
  • 19 Sep, 2021
  • 59 locations
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

This study will assess the effect of lowering low-density lipoprotein cholesterol (LDL-C) with evolocumab on major cardiovascular events in adults without a prior myocardial infarction (MI) or stroke who are at high risk of a cardiovascular event.

stroke
myocardial infarction
infarct
arterial disease
diabetes
  • 542 views
  • 19 Sep, 2021
  • 1333 locations
Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction

A Phase IIB Parallel group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants with a Prior Myocardial Infarction.

myocardial infarction
infarct
  • 0 views
  • 16 Sep, 2021
  • 69 locations
Impella -Supported PCI in High-Risk Patients With Complex Coronary Artery Disease and Reduced Left Ventricular Function

The purpose of this study is to assess if using the Impella CP (or Impella 2.5) device during high-risk PCI in patients with reduced left-sided heart function will result in an improvement in symptoms, heart function and health after a heart procedure compared to the current standard of care.

exercise stress test
ischemia
infarct
clot
in stent restenosis
  • 0 views
  • 15 Sep, 2021
  • 40 locations
The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

The purpose is to compare median two-year clinical outcome after OCT guided vs. standard guided revascularization of patients requiring complex bifurcation stent implantation

revascularisation
angina pectoris
stable angina
stemi
ischemia
  • 355 views
  • 19 Sep, 2021
  • 80 locations