Severe Short Stature Clinical Trials

A listing of Severe Short Stature medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 39 clinical trials
Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children

This study evaluates the safety and efficiency of Pegylated Somatropin (PEG Somatropin) Injection in the treatment of endogenous growth hormone deficiency (GHD) in the broad population of children. Half of participants will receive the high dose, while the other half will receive the low dose.

growth hormone
deficiency
somatropin
stimulation test
  • 5 views
  • 07 Nov, 2020
  • 1 location
Extension Study of Pegylated Somatropin to Treat Growth Retardation Caused by Endogenous Growth Hormone Deficiency in Children

influencing the efficacy of PEG-Somatropin and to establish the height prediction model based on Chinese children with short stature, and to provide the basis and guidance for standard and reasonable long

  • 4 views
  • 21 Jan, 2021
  • 1 location
A Study Of Safety Tolerability And Effectiveness Of Recifercept In Children With Achondroplasia

Approximately 63 participants will be randomized to one of three doses to receive Recifercept either Low Dose Medium Dose High Dose Participants will will attend the clinic at baseline and at Day 1, 4, 8, 15, 29 & then Month 2, 3 6, 9 & 12. Assessments include safety, blood …

testicular
  • 0 views
  • 30 Jul, 2021
  • 11 locations
Albright Hereditary Osteodystrophy: Natural History Growth and Cognitive/Behavioral Assessments

FD003409, IND 67148 or those who meet the criteria of idiopathic short stature or SGA. We are also evaluating neurocognitive and psychosocial functioning in participants with AHO in order to

  • 110 views
  • 24 Jan, 2021
  • 1 location
Vosoritide for Selected Genetic Causes of Short Stature

Short stature can be caused by a number of genetic etiologies, many of which directly affect the growth plate. The FGFR3/CNP pathway is central to growth of the chondrocyte. The study team

vosoritide
mras
stimulation test
saddan syndrome
testicular
  • 2 views
  • 10 May, 2021
  • 1 location
Efficacy and Safety of rhGH (Jintropin ) in Pediatric Participants With ISS

Phase 1: To evaluate the safety and efficacy of 0.05mg/kg/d of rhGH (Jintropin) in the treatment of children with idiopathic short stature (ISS) in 52 weeks. Phase 2: To evaluate the

somatropin
somatotropin
hormone therapy
growth hormone
growth hormone treatment
  • 7 views
  • 22 Jan, 2021
  • 5 locations
A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Short Stature Children Due to Chronic Kidney Disease Before Transplantation

This study aims to evaluate the efficacy and safety of recombinant human growth hormone injection in short stature children due to chronic kidney disease before transplantation.

growth hormone treatment
osteopathy
somatotropin
somatropin
growth hormone
  • 10 views
  • 22 Jan, 2021
  • 7 locations
A Study Extension Period of PEG-somatropin (Pegylated-somatropin) in the Treatment of Children With Idiopathic Short Stature

strategy is used to treat children with ISS (Idiopathic Short Stature). The long-term efficacy and safety of the investigational product are evaluated, which can provide more scientific and reliable

igf-i
growth hormone
somatotropin
somatropin
  • 34 views
  • 21 Jan, 2021
  • 2 locations
Study of Infigratinib in Children With Achondroplasia

This is a Phase 2, multicenter, open-label, dose-escalation and dose-expansion study to evaluate the safety, tolerability, and efficacy of infigratinib, a fibroblast growth factor receptor (FGFR) 1-3-selective tyrosine kinase inhibitor, in children 3 to 11 years of age with Achondroplasia (ACH) who previously participated in the PROPEL study (Protocol QBGJ398-001) …

tyrosine kinase inhibitor
  • 8 views
  • 30 Jul, 2021
  • 5 locations
A Clinical Trial to Evaluate Safety of Vosoritide in At-risk Infants With Achondroplasia

Study 111-209 is a Phase 2 randomized, open-label clinical trial of BMN 111 in infants and young children with a diagnosis of Achondroplasia at a heightened risk of requiring cervicomedullary decompression surgery

  • 0 views
  • 02 Aug, 2021
  • 3 locations