Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 217 clinical trials
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapy(BAT)in adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.

immunosuppressant
azathioprine
thrombocytopenia
cyclosporine
platelet count
  • 0 views
  • 26 May, 2022
  • 1 location
Avatrombopag in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies

This prospective, open-label, single-center, one-arm clinical trial aims at evaluating the efficacy and safety of avatrombopag in Chinese adult Immune Thrombocytopenia (ITP) patients with autoantibodies fail (due to intolerance or resistance) to eltrombopag or herombopag treatment.

evans syndrome
thrombocytopenia
glucocorticoids
sjogren's syndrome
platelet count
  • 0 views
  • 04 Oct, 2022
  • 1 location
An Open-label Study of Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

Background Dermatomyositis (DM) and juvenile dermatomyositis (JDM) cause inflammation in the muscles. People with DM and JDM can develop calcium deposits in places they should not, known as calcinosis. Calcinosis can be painful and cause disabilities and other problems. Researchers want to learn more about calcinosis to find treatments for …

diabetes
myositis
urine tests
calcium
igiv
  • 190 views
  • 22 Oct, 2022
  • 1 location
Baricitinib in Patients With Relapsing or naïve Dermatomyositis (BIRD)

Dermatomyositis (DM) is a rare and disabling condition with an important impairment of quality of life and possible life-threatening complications. Treatment is based on high doses of corticosteroids but this exposes patients to adverse events (cardiovascular mortality, glucocorticoids-induced muscle and skin damages). Corticosteroids taper is associated with disease relapses. Although …

methotrexate
glucocorticoids
corticosteroids
dermatomyositis
disease modifying antirheumatic drugs
  • 0 views
  • 07 Oct, 2022
  • 1 location
High-dose Cephalexin for Cellulitis (HI-DOCC) (HI-DOCC)

Cellulitis is a common condition diagnosed and managed in the ED that carries significant burden on healthcare systems globally. Cellulitis is the 8th most common reason patients present to an ED in Canada. Among middle-aged patients (45-64 years) it is the 5th most common reason to visit an ED. This …

Accepts healthy volunteers
  • 0 views
  • 30 Sep, 2023
  • 1 location
Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture - a Randomised Controlled Multicenter Trial

Dupuytren's contracture (DC) is associated with progressive finger flexion and extension deficit caused by fibrosis in the palm and digits. Treatment options include minimally invasive procedures such as percutaneous needle fasciotomy (PNF) and collagenase clostridium histolyticum injections as well as open fasciectomy. PNF has recently become more popular in Sweden …

Accepts healthy volunteers
  • 0 views
  • 14 Oct, 2022
  • 1 location
Pelvic CT With Agatston Calcium Score for Peyronie Disease

The purpose of this study is to find out how including a CT exam of the penis can help urologists make treatment decisions for patients with calcified Peyronie's disease.

  • 0 views
  • 17 Sep, 2023
  • 1 location
Study Evaluating Efficacy and Safety of Froniglutide (PF1801) in Patients With Idiopathic Inflammatory Myopathy (FROG)

This is a Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Froniglutide in Patients With Idiopathic Inflammatory Myopathy ("FROniGlutide Study")

  • 0 views
  • 19 Sep, 2023
  • 1 location
Centrally Acting ACE Inhibition in SLE

SLE is a chronic autoimmune disease that often involves multiple systems and organs of the body. An autoimmune disease is one which your immune system attacks the cells and tissues in different parts of the body. SLE is characterized by inflammation that leads to tissue damage in many different organ …

diabetes
18f-fdg
corticosteroids
autoimmune disease
sjogren's syndrome
  • 0 views
  • 29 Nov, 2021
  • 7 locations
Exercise and Nutrition Recommendations for Patients Using Glucocorticoids (ENRG)

This parallel-group randomized, controlled, clinical trial aims to investigate the influence of a 6-month home-based, remotely-monitored, exercise training intervention on musculoskeletal health in patients with Systemic Lupus Erythematosus who have undergone glucocorticoid pulse therapy.

lupus
glucocorticoids
  • 0 views
  • 29 Oct, 2021
  • 1 location