Connective Tissue Diseases Clinical Trials
A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 213 clinical trials
Immune Mediators and Metabolites to Stratify Systemic Lupus Erythematosus Patients at High Risk of Cardio Vascular Diseases (ISLE)
Accelerated atherosclerosis is an established complication of systemic autoimmune diseases, particularly SLE. Young female patients with SLE are more likely to develop myocardial infarction than matched healthy controls, and CVD is nowadays one of the most common causes of death (27%) in lupus patients. While traditional CV risk factors cannot …
- 0 views
- 04 Oct, 2022
- 2 locations
Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE (NAIVE)
This study to examines the impact of anifrolumab on disease activity, immune phenotypes, and development of neutralizing antibodies to quadrivalent influenza vaccine in patients with Systemic Lupus Erythematosus (SLE). 10 patients with moderately to severely active SLE will be treated with anifrolumab in addition to standard of care lupus treatments …
- 0 views
- 10 Apr, 2023
- 1 location
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema (Lipedema)
Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid. Little is known about the functional changes that lead to fat accumulation and pain in women with …
- 331 views
- 12 Aug, 2023
- 1 location
Immunosuppressant Combined With Pirfenidone in CTD-ILD
A prospective cohort study was used to observe the efficacy and safety of different immunosuppressive agents with/wo pirfenidone on CTD-ILD patients in Qilu Hospital of Shandong University for 36 months.The main research endpoints are lung function, patient dyspnea score, 6-minute walking distance, imaging indicators, primary disease activity, adverse reactions, etc.
- 2 views
- 24 Jun, 2021
- 1 location
Efficacy,Immune Function of Pirfenidone in the Treatment of Connetive Tissue Disease -Ralated Interstitial Lung Disease(CTD-LID)
A single-center randomized controlled study was used to observe the efficacy and immune function with/wo pirfenidone on CTD-ILD patients in QIlu Hospital of Shanndong University for 24 months. 2:1 randomization was performed。The main research endpoints are lung function.
- 0 views
- 17 Oct, 2022
- 1 location
Novel Form of Acquired Long QT Syndrome
The goal of this study is to determine whether anti-Ro/SSA antibodies are associated with acquired QT prolongation in subjects with connective tissue disease. The investigators will investigate
- 4 views
- 20 Apr, 2022
- 1 location
Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre
Systemic sclerosis (SSc) is a rare form of connective tissue disease characterized by vascular involvement and the intensity of fibrosis. The lack of available treatment is largely due to the
- 0 views
- 16 May, 2021
- 1 location
Exercise Capacity of Patients With Dermatomyosis (MIDE)
Dermatomyositis (DM) patients experience muscle weakness and low aerobic capacities, which are associated with poor health status and increased mortality. The origin of this muscle impairment remains unknown. The investigators hypothesize that mitochondria functioning is impaired in DM muscle and links with exercise capacities.
- 0 views
- 26 Aug, 2023
- 1 location
Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis
This is a 52 week, single center, randomized, double-blind, placebo-controlled study. After patients maintain a stable dose of Mycophenolate Mofetil (MMF) for at least 1 month, they will be randomized to treatment with either Belimumab & Rituximab or placebo.Patients in both groups will be on background MMF for the entirety …
- 29 views
- 20 Sep, 2023
- 1 location
Eltrombopag Combined With Low-dose Rituximab in the Treatment of Adult Immune Thrombocytopenia With Autoantibodies
This prospective, open-label, nonrandomized, multicenter clinical trial aims at comparing the efficacy and safety of combined use of eltrombopag with low-dose rituximab vs. the best available therapy（BAT）in adult immune thrombocytopenia with autoantibodies fail (due to intolerance or resistance) to first-line treatment.
- 0 views
- 26 May, 2022
- 1 location