Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 732 clinical trials
Effect of Ketosis on Pain and Quality of Life in Patients With Lipedema

Lipedema is a female progressive fat disorder, characterized by a symmetrical increase in subcutaneous adipose tissue in the lower extremities with the exception of the waist. The condition is often misdiagnosed and underdiagnosed. The etiology is poorly understood. Affects about 11% of all women and may lead to pain and …

  • 0 views
  • 02 Apr, 2021
  • 2 locations
The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, …

palmar fasciectomy
discomfort
dupuytren's contracture
scarring
fasciotomy
  • 841 views
  • 13 Jun, 2021
  • 1 location
Phase 2 Trial of Mesenchymal Stem Cells in Systemic Lupus Erythematosus (MiSLE)

The purpose of this study is to evaluate the efficacy and safety of mesenchymal stem cells (MSCs) obtained from umbilical cords for the treatment of adults with systemic lupus erythematosus (SLE). The goal of this study is to determine if patients receiving an MSC infusion plus standard of care respond …

nephritis
azathioprine
lupus
cyclophosphamide
mycophenolate
  • 153 views
  • 17 Apr, 2021
  • 9 locations
Effect of Curcumin on Systemic Lupus Erythematosus

The purpose of this investigator initiated study is to determine the efficacy of curcumin on disease activity of subjects with systemic lupus erythematous. Curcumin has been found to have anti-inflammatory effects and has been found to improve disease activity in lupus patients. In addition, subjects with rheumatoid arthritis as well …

treatment regimen
lupus
arthritis
  • 3 views
  • 21 May, 2021
  • 1 location
Study of Anti-Malarials in Incomplete Lupus Erythematosus

This project is a multicenter, randomized, placebo-controlled, double-blind clinical trial that is designed to test whether treating patients who are at risk for development of lupus with hydroxychloroquine can slow accumulation of disease features. Effects on clinical progression of symptoms, patient-reported outcomes and changes in the immune markers of response …

hydroxychloroquine
antinuclear antibody
arthritis
lupus
antimalarials
  • 114 views
  • 26 Jan, 2021
  • 7 locations
A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)

The purpose of the study is to assess the Safety, Tolerability, PK/PD and preliminary Efficacy of ICP-022 in Subjects with Systemic Lupus Erythematosus (SLE)

antinuclear antibody
lupus
  • 0 views
  • 31 May, 2021
  • 13 locations
Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter Randomised Placebo-controlled Trial

The management of active systemic lupus erythematosus (SLE) is challenging due to the heterogeneous nature of the disease and lack of specific treatment. Current treatment regimens mainly rely on corticosteroids and immunosuppressive agents which are associated with substantial adverse effects including various infections. Therefore, there is an unmet need for …

hydroxychloroquine
lupus
cyclophosphamide
interleukin-2
immunosuppressive agents
  • 5 views
  • 24 Jan, 2021
  • 1 location
The Safety and Efficacy of Zishenqing in Subjects With Active Systemic Lupus Erythematosus

This study evaluates the safety and efficacy of the traditional chinese medicine Zishenqing in the treatment of active systemic lupus erythematosus.

treatment regimen
corticosteroids
hydroxychloroquine
azathioprine
methotrexate
  • 0 views
  • 24 Jan, 2021
  • 1 location
The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 on Children With Rheumatic Diseases

The study aims to explore the therapeutic value and mechanism of Interleukin-2 on children with rheumatic diseases (Systemic Lupus Erythematosus, Primary Sjgren Syndrome, Juvenile Idiopathic Arthritis).

sjogren's syndrome
arthritis
lupus
interleukin-2
rheumatic diseases
  • 0 views
  • 26 Jan, 2021
  • 1 location
O-GlcNAcylation Role in the Pathophysiology of Systemic Lupus Erythematosus

This study aims at defining the role of O-GlcNAcylation is in the physiopathology of systemic lupus erythematosus (SLE). O-GlcNAcylation is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.

lupus
  • 0 views
  • 26 Jan, 2021
  • 1 location